Macrophage Cell Death Upon Intracellular Bacterial Infection

Overview

Journal Macrophage (Houst)

Date 2015 Dec 23

PMID 26690967

Citations 4

Authors

Xin-He Lai

Yunsheng Xu

Xiao-Ming Chen

Yi Ren

Affiliations

Soon will be listed here.

Abstract

Macrophage-pathogen interaction is a complex process and the outcome of this tag-of-war for both sides is to live or die. Without attempting to be comprehensive, this review will discuss the complexity and significance of the interaction outcomes between macrophages and some facultative intracellular bacterial pathogens as exemplified by and . Upon bacterial infection, macrophages can die by a variety of ways, such as apoptosis, autophagic cell death, necrosis, necroptosis, oncosis, pyronecrosis, pyroptosis , which is the focus of this review.

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