Challenges with Diagnosing and Managing Sepsis in Older Adults

Overview

Journal Expert Rev Anti Infect Ther

Specialty Infectious Diseases

Date 2015 Dec 22

PMID 26687340

Citations 38

Authors

Kalin M Clifford

Eliza A Dy-Boarman

Krystal K Haase

Kristen Maxvill

Steven E Pass

Carlos A Alvarez

Affiliations

Soon will be listed here.

Abstract

Sepsis in older adults has many challenges that affect rate of septic diagnosis, treatment, and monitoring parameters. Numerous age-related changes and comorbidities contribute to increased risk of infections in older adults, but also atypical symptomatology that delays diagnosis. Due to various pharmacokinetic/pharmacodynamic changes in the older adult, medications are absorbed, metabolized, and eliminated at different rates as compared to younger adults, which increases risk of adverse drug reactions due to use of drug therapy needed for sepsis management. This review provides information to aid in diagnosis and offers recommendations for monitoring and treating sepsis in the older adult population.

Citing Articles

Sepsis in Aging Populations: A Review of Risk Factors, Diagnosis, and Management.

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Factors Affecting Continuous Renal Replacement Therapy (CRRT) in Patients With Septic Shock: An Analysis of a National Inpatient Sample Database.

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Deep reinforcement learning extracts the optimal sepsis treatment policy from treatment records.

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Malnutrition and Its Influence on Sepsis Outcomes in Elderly Patients.

Daud M, Ullah F, Uzair M, Siddiq A, Siddiq U, Riaz F Cureus. 2024; 16(6):e63433.

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