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Comparative Clinical Evaluation of Glycosylated Haemoglobin Level in Healthy and Chronic Periodontitis Patients: A Chairside Diagnostic Method

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Specialty Dentistry
Date 2015 Dec 18
PMID 26672421
Citations 4
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Abstract

Objective And Background: Glycosylated haemoglobin (HbA1c) level can consequently be interpreted as an average of the blood glucose present over the past 3-4 months. Periodontitis is associated with glycemic control in patients with diabetes. The purpose of this study was to determine the level of HbA1c in healthy and periodontitis patients who were previously not diagnosed with diabetes mellitus.

Materials And Methods: A total of 40 patients were selected for study and divided into two groups. Group 1 included patients with a healthy periodontium, and Group 2 included patients suffering from chronic periodontitis. Finger stick blood was collected by special collection unit (A1CNOW+® Bayer Health Care, Tarrytown New York, USA), for estimating level of HbA1c.

Result: Both groups showed similar HbA1c levels clinically with slight increase in levels in the test group, but was statistically significant (test--5.66 ± 0.35%, control--5.17 ± 0.3% P = 0.003).

Conclusion: Indians are at a high-risk of developing periodontitis and diabetes. These data suggest a possible link between periodontitis and glycemic control in nondiabetic individuals, periodontal disease may be a potential contributor to the development of type 2 diabetes.

Citing Articles

Association between Periodontitis and HbA1c Levels in Non-Diabetic Patients: A Systematic Review and Meta-Analysis.

Zhao D, Sun Y, Li X, Wang X, Lu L, Li C Healthcare (Basel). 2023; 11(19).

PMID: 37830686 PMC: 10572398. DOI: 10.3390/healthcare11192649.


A pilot study on glycemia and insulin resistance in patients with severe periodontitis.

George A, Narayan V, Kurian N, Joseph A, Anil S J Indian Soc Periodontol. 2021; 25(5):393-398.

PMID: 34667381 PMC: 8452164. DOI: 10.4103/jisp.jisp_419_20.


Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome.

Pirih F, Monajemzadeh S, Singh N, Sinacola R, Shin J, Chen T Periodontol 2000. 2021; 87(1):50-75.

PMID: 34463996 PMC: 8457155. DOI: 10.1111/prd.12379.


Screening for dysglycaemia in dental primary care practice settings: systematic review of the evidence.

Glurich I, Bartkowiak B, Berg R, Acharya A Int Dent J. 2018; 68(6):369-377.

PMID: 29740815 PMC: 9379002. DOI: 10.1111/idj.12405.