Drug Therapy for Behavioral and Psychological Symptoms of Dementia

Overview

Journal Curr Neuropharmacol

Publisher Bentham Science Publishers

Date 2015 Dec 9

PMID 26644152

Citations 14

Authors

Feng Wang

Ting-Yi Feng

Shilin Yang

Maurice Preter

Jiang-Ning Zhou

Xiao-Ping Wang

Affiliations

Soon will be listed here.

Abstract

Dementia, which can be induced by diverse factors, is a clinical syndrome characterized by the decline of cognitive function. Behavioral and psychological symptoms of dementia (BPSD) include depression, agitation, and aggression. Dementia causes a heavy burden on patients and their caregivers. Patients with BPSD should be assessed comprehensively by practitioners and offered appropriate non-pharmacologic and pharmacologic therapy. Nonpharmacologic therapy has been recommended as the basal treatment for BPSD; however, pharmacologic therapy is required under many situations. Medications, including antipsychotic agents, antidepressants, sedative and hypnotic agents, mood stabilizers, cholinesterase inhibitors, and amantadine, are extensively used in clinical practice. We have reviewed the progression of pharmacologic therapy for BPSD.

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