Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research

Overview

Journal Trends Microbiol

Date 2015 Dec 9

PMID 26642901

Citations 44

Authors

Cynthia I Grossman

Anna Laura Ross

Judith D Auerbach

Jintanat Ananworanich

Karine Dube

Joseph D Tucker

Veronica Noseda

Cristina Possas

Dianne M Rausch

Affiliations

Soon will be listed here.

Abstract

The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.

Citing Articles

Innovative Diagnostic Approaches and Challenges in the Management of HIV: Bridging Basic Science and Clinical Practice.

Afzal M, Agarwal S, Elshaikh R, Babker A, Osman E, Choudhary R Life (Basel). 2025; 15(2).

PMID: 40003618 PMC: 11856619. DOI: 10.3390/life15020209.

'It is scary to pause treatment': perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa.

Mthimkhulu D, Dong K, Ngcobo M, Mindry D, Zulu A, Langa N HIV Res Clin Pract. 2025; 26(1):2455917.

PMID: 39862155 PMC: 11829625. DOI: 10.1080/25787489.2025.2455917.

HIV Clinical Providers' Awareness, Attitudes, and Willingness to Support Patient Outreach Efforts for HIV Cure-Directed Research in Philadelphia, United States.

Meanley S, Carter W, Short W, Metzger D, Onorato A, Montaner L Open Forum Infect Dis. 2024; 11(12):ofae687.

PMID: 39660018 PMC: 11631357. DOI: 10.1093/ofid/ofae687.

"This Is Actually a Really Unique Moment in Time": Navigating Long-Acting HIV Treatment and HIV Cure Research with Analytical Treatment Interruptions-A Qualitative Interview Study in the United States.

Dube K, Perez-Brumer A, Patel H, Zhou C, Dee L, Graham G AIDS Res Hum Retroviruses. 2024; 40(8):455-463.

PMID: 38386494 PMC: 11386995. DOI: 10.1089/AID.2023.0105.

Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States.

Bilger A, Plenn E, Barg F, Rendle K, Carter W, Lamour-Harrington A HIV Res Clin Pract. 2023; 24(1):2267825.

PMID: 37837376 PMC: 10634456.

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