Serum MicroRNAs As Potential Noninvasive Biomarkers for Glioma

Overview

Journal Tumour Biol

Publisher Sage Publications

Specialty Oncology

Date 2015 Dec 3

PMID 26628296

Citations 9

Authors

Xin Yu

Zheng Li

Affiliations

Soon will be listed here.

Abstract

Gliomas are derived from astroglial precursors or astrocytes, accounting for 40 % central nervous system tumors. MicroRNAs (miRNAs) are a class of endogenous, small (19- to 23-nucleotides) non-coding RNAs involved in cancer progression. Recent studies show that circulating miRNAs are associated with the clinicopathological features and prognosis of gliomas. Serum miRNAs may serve as novel biomarkers for gliomas diagnosis. This review explores the possibilities of using serum miRNAs as prognostic, diagnostic markers, and therapeutic targets in gliomas.

Citing Articles

Construct of qualitative diagnostic biomarkers specific for glioma by pairing serum microRNAs.

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Inhibition of lncRNA LINC00461/miR-216a/aquaporin 4 pathway suppresses cell proliferation, migration, invasion, and chemoresistance in glioma.

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