Sinonasal Phosphaturic Mesenchymal Tumor: A Rare and Misinterpreted Entity

Overview

Journal J Neurol Surg Rep

Publisher Thieme

Date 2015 Dec 2

PMID 26623233

Citations 3

Authors

Demetri Arnaoutakis

Iman Naseri

Affiliations

Soon will be listed here.

Abstract

Objectives Oncogenic osteomalacia is a paraneoplastic syndrome in which the tumor secretes a peptide-like hormone, fibroblast growth factor, resulting in urinary loss of phosphates. Methods We present the case of a 50-year-old woman with a benign phosphaturic mesenchymal tumor (PMT) involving the ethmoid sinus with obstruction of the ostiomeatal complex causing unilateral nasal airway obstruction. Results The tumor was initially thought to be an esthesioneuroblastoma based on primary pathology interpretation and on clinical and radiographic appearance. However, a benign PMT was later confirmed by further testing. Conclusion The tumor was removed entirely by the endoscopic transnasal approach, leading to a full resolution of symptoms.

Citing Articles

Phosphaturic Mesenchymal Tumors from Head to Toe: Imaging Findings and Role of the Radiologist in Diagnosing Tumor-Induced Osteomalacia.

Kawthalkar A, Janu A, Deshpande M, Gala K, Gulia A, Puri A Indian J Orthop. 2020; 54(2):215-223.

PMID: 32257040 PMC: 7096593. DOI: 10.1007/s43465-019-00005-5.

Tumor induced osteomalacia in head and neck region: single center experience and systematic review.

Shah R, Lila A, Jadhav R, Patil V, Mahajan A, Sonawane S Endocr Connect. 2019; 8(10):1330-1353.

PMID: 31505461 PMC: 6790902. DOI: 10.1530/EC-19-0341.

Oncogenic Osteomalacia with Elevated Fibroblast Growth Factor 23: A Rare Case of Paranasal Sinus Tumor Onset.

Rigante M, Loperfido A, Paludetti G Cureus. 2019; 11(6):e4919.

PMID: 31423395 PMC: 6692094. DOI: 10.7759/cureus.4919.

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