Systemic Lupus Erythematosus with Intestinal Perforation: A Case Report

Overview

Journal Exp Ther Med

Specialty Pathology

Date 2015 Dec 2

PMID 26622471

Citations 5

Authors

Yuqing Gu

Tao Zhu

Yiqing Wang

Hongxing Xu

Affiliations

Soon will be listed here.

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease, which can affect almost all systems and organs. Gastrointestinal disorder is one of the most noteworthy complications of patients with SLE. However, gastrointestinal disorder with intestinal perforation is rare, but potentially life-threatening if not treated promptly. The present study reported a case of SLE with intestinal perforation, where surgical intervention was performed and a crevasse (~3 cm in diameter) was detected in the ileum, ~60 cm from the ileocecal valve. Following surgery, the patient suffered from difficult ventilator weaning, septic shock and intestinal obstruction. The patient was successfully treated and discharged from the hospital after ~4 months of treatment. Intestinal perforation in SLE patients is potentially life-threatening; early diagnosis and prompt treatment are crucial to the management of this rare complication of SLE.

Citing Articles

Intestinal perforation with systemic lupus erythematosus: A systematic review.

Chen Y, Meng J, Li C Medicine (Baltimore). 2023; 102(31):e34415.

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Surgical treatment of acute aortic dissection in a patient with SLE and prior antiphospholipid syndrome on therapy for over 30 years: a case report.

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Stercoral Perforation of Sigmoid Colon in Systemic Lupus Erythematosus: A Rare Cause of Peritonitis.

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Lupus causing small bowel obstruction.

Yang Y, Bartsch A, Fryer E, Hancu D BMJ Case Rep. 2018; 2018.

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