Cinacalcet-associated Severe Hypocalcemia Resulting in Torsades De Pointes and Cardiac Arrest: a Case for Caution

Overview

Journal Eur J Clin Pharmacol

Specialty Pharmacology

Date 2015 Dec 2

PMID 26621501

Citations 4

Authors

Tessa Novick

Blaithin A McMahon

Adam Berliner

Bernard G Jaar

Affiliations

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Citing Articles

Severe Symptomatic Hypocalcemia, complicating cardiac arrhythmia following Cinacalcet (Sensipar) administration: A Case Report.

Schmidt G, Weaver T, Hoang T, Shakir M Clin Case Rep. 2021; 9(10):e04876.

PMID: 34659755 PMC: 8502441. DOI: 10.1002/ccr3.4876.

Cinacalcet-Associated Resolution of Primary Hyperparathyroidism in a Patient With Normal Kidney Function.

Nguyen S, Gosmanova E, Gosmanov A J Investig Med High Impact Case Rep. 2020; 8:2324709620936836.

PMID: 32583691 PMC: 7318811. DOI: 10.1177/2324709620936836.

Cinacalcet-induced hypocalcemia in a cohort of European haemodialysis patients: predictors, therapeutic approaches and outcomes.

Louie K, Erhard C, Wheeler D, Stenvinkel P, Fouqueray B, Floege J J Nephrol. 2019; 33(4):803-816.

PMID: 31848883 PMC: 7381480. DOI: 10.1007/s40620-019-00686-z.

Hungry bone syndrome two weeks after starting cinacalcet: a call for caution.

Koubar S, Qannus A, Medawar W, Abu-Alfa A CEN Case Rep. 2017; 7(1):21-23.

PMID: 29124559 PMC: 5886916. DOI: 10.1007/s13730-017-0284-z.

References

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Messa P, Macario F, Yaqoob M, Bouman K, Braun J, von Albertini B . The OPTIMA study: assessing a new cinacalcet (Sensipar/Mimpara) treatment algorithm for secondary hyperparathyroidism. Clin J Am Soc Nephrol. 2008; 3(1):36-45. PMC: 2390975. DOI: 10.2215/CJN.03591006. View

Borrego-Utiel F, Perez-del Barrio M, Biechy-Baldan M, Segura-Torres P . Cinacalcet may prolong the QT interval in patients on haemodialysis with secondary hyperparathyroidism. Nefrologia. 2013; 33(2):272-3. DOI: 10.3265/Nefrologia.pre2012.Oct.11679. View

Soroker D, Ezri T, Szmuk P, Merlis P, Epstein M, Caspi A . Perioperative torsade de pointes ventricular tachycardia induced by hypocalcemia and hypokalemia. Anesth Analg. 1995; 80(3):630-3. DOI: 10.1097/00000539-199503000-00039. View