Recovery Potential After Acute Stroke

Overview

Journal Front Neurol

Specialty Neurology

Date 2015 Dec 1

PMID 26617568

Citations 27

Authors

Rudiger J Seitz

Geoffrey A Donnan

Affiliations

Soon will be listed here.

Abstract

In acute stroke, the major factor for recovery is the early use of thrombolysis aimed at arterial recanalization and reperfusion of ischemic brain tissue. Subsequently, neurorehabilitative training critically improves clinical recovery due to augmention of postlesional plasticity. Neuroimaging and electrophysiology studies have revealed that the location and volume of the stroke lesion, the affection of nerve fiber tracts, as well as functional and structural changes in the perilesional tissue and in large-scale bihemispheric networks are relevant biomarkers of post-stroke recovery. However, associated disorders, such as mood disorders, epilepsy, and neurodegenerative diseases, may induce secondary cerebral changes or aggravate the functional deficits and, thereby, compromise the potential for recovery.

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References

Rusconi E, Pinel P, Eger E, Lebihan D, Thirion B, Dehaene S . A disconnection account of Gerstmann syndrome: functional neuroanatomy evidence. Ann Neurol. 2009; 66(5):654-62. DOI: 10.1002/ana.21776. View

Ebrahim S, Nouri F, Barer D . Cognitive impairment after stroke. Age Ageing. 1985; 14(6):345-8. DOI: 10.1093/ageing/14.6.345. View

Dancause N, Barbay S, Frost S, Plautz E, Chen D, Zoubina E . Extensive cortical rewiring after brain injury. J Neurosci. 2005; 25(44):10167-79. PMC: 6725801. DOI: 10.1523/JNEUROSCI.3256-05.2005. View

Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick J . Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004; 363(9411):768-74. DOI: 10.1016/S0140-6736(04)15692-4. View

McCombe P, Read S . Immune and inflammatory responses to stroke: good or bad?. Int J Stroke. 2008; 3(4):254-65. DOI: 10.1111/j.1747-4949.2008.00222.x. View

Lang C, Schieber M . Reduced muscle selectivity during individuated finger movements in humans after damage to the motor cortex or corticospinal tract. J Neurophysiol. 2003; 91(4):1722-33. DOI: 10.1152/jn.00805.2003. View

Igo Krebs H, Volpe B, Hogan N . A working model of stroke recovery from rehabilitation robotics practitioners. J Neuroeng Rehabil. 2009; 6:6. PMC: 2649944. DOI: 10.1186/1743-0003-6-6. View

KRETSCHMANN H . Localisation of the corticospinal fibres in the internal capsule in man. J Anat. 1988; 160:219-25. PMC: 1262065. View

Arboix A, Comes E, Garcia-Eroles L, Massons J, Oliveres M, Balcells M . Prognostic value of very early seizures for in-hospital mortality in atherothrombotic infarction. Eur Neurol. 2003; 50(2):78-84. DOI: 10.1159/000072503. View

10.

Schafer R, Popp K, Jorgens S, Lindenberg R, Franz M, Seitz R . Alexithymia-like disorder in right anterior cingulate infarction. Neurocase. 2007; 13(3):201-8. DOI: 10.1080/13554790701494964. View

11.

Schaechter J, Fricker Z, Perdue K, Helmer K, Vangel M, Greve D . Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patients. Hum Brain Mapp. 2009; 30(11):3461-74. PMC: 2780023. DOI: 10.1002/hbm.20770. View

12.

Seitz R, Sukiennik J, Siebler M . Outcome after systemic thrombolysis is predicted by age and stroke severity: an open label experience with recombinant tissue plasminogen activator and tirofiban. Neurol Int. 2012; 4(2):e9. PMC: 3490474. DOI: 10.4081/ni.2012.e9. View

13.

Sacco S, Ornello R, Ripa P, Pistoia F, Carolei A . Migraine and hemorrhagic stroke: a meta-analysis. Stroke. 2013; 44(11):3032-8. DOI: 10.1161/STROKEAHA.113.002465. View

14.

Perez M, Cohen L . Mechanisms underlying functional changes in the primary motor cortex ipsilateral to an active hand. J Neurosci. 2008; 28(22):5631-40. PMC: 2440822. DOI: 10.1523/JNEUROSCI.0093-08.2008. View

15.

Delgado-Mederos R, Rovira A, Alvarez-Sabin J, Ribo M, Munuera J, Rubiera M . Speed of tPA-induced clot lysis predicts DWI lesion evolution in acute stroke. Stroke. 2007; 38(3):955-60. DOI: 10.1161/01.STR.0000257977.32525.6e. View

16.

de Laat K, van Norden A, Gons R, van Uden I, Zwiers M, Bloem B . Cerebral white matter lesions and lacunar infarcts contribute to the presence of mild parkinsonian signs. Stroke. 2012; 43(10):2574-9. DOI: 10.1161/STROKEAHA.112.657130. View

17.

Seitz R, Meisel S, Weller P, Junghans U, Wittsack H, Siebler M . Initial ischemic event: perfusion-weighted MR imaging and apparent diffusion coefficient for stroke evolution. Radiology. 2005; 237(3):1020-8. DOI: 10.1148/radiol.2373041435. View

18.

Lindberg P, Schmitz C, Engardt M, Forssberg H, Borg J . Use-dependent up- and down-regulation of sensorimotor brain circuits in stroke patients. Neurorehabil Neural Repair. 2007; 21(4):315-26. DOI: 10.1177/1545968306296965. View

19.

Kuroda S, Houkin K . Moyamoya disease: current concepts and future perspectives. Lancet Neurol. 2008; 7(11):1056-66. DOI: 10.1016/S1474-4422(08)70240-0. View

20.

Prochnow D, Bermudez I Badia S, Schmidt J, Duff A, Brunheim S, Kleiser R . A functional magnetic resonance imaging study of visuomotor processing in a virtual reality-based paradigm: Rehabilitation Gaming System. Eur J Neurosci. 2013; 37(9):1441-7. DOI: 10.1111/ejn.12157. View