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Zolpidem Test and Catatonia

Overview
Specialties Pharmacology
Pharmacy
Date 2015 Nov 9
PMID 26547135
Citations 3
Authors
Affiliations
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Abstract

What Is Known And Objective: There is no consensus regarding treatment of catatonia and the main recent therapeutic progress has been the development of the zolpidem diagnostic and therapeutic test. We report on the use of this test in one of our patients.

Cases Summary: Mr. S. suffered from a paranoid schizophrenia. Three episodes of catatonia are described to illustrate the effect of zolpidem in a patient for whom lorazepam was ineffective or inadequate.

What Is New And Conclusion: Zolpidem with appropriate testing appears to be a credible alternative to electroconvulsive therapy or increased lorazepam dosing and allows continuation of antipsychotic administration.

Citing Articles

Psychopharmacology of Catatonia: A Tour D'horizon.

Naguy A, Pridmore S, Ozidu V, Alamiri B Psychopharmacol Bull. 2025; 55(1):64-69.

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Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology.

Rogers J, Oldham M, Fricchione G, Northoff G, Wilson J, Mann S J Psychopharmacol. 2023; 37(4):327-369.

PMID: 37039129 PMC: 10101189. DOI: 10.1177/02698811231158232.


Lorazepam-Resistant Catatonia in an Antipsychotic-Naïve 24-Year-Old with Psychotic Symptoms.

Lucchelli J, Kourakou S, Perez de Lucia Bove L, Rodriguez D Case Rep Psychiatry. 2020; 2020:2469707.

PMID: 32318305 PMC: 7165349. DOI: 10.1155/2020/2469707.