Antineutrophil Cytoplasm Antibodies in Kawasaki Disease

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 1989 Mar 1

PMID 2650637

Citations 19

Authors

C O Savage

J Tizard

D Jayne

C M Lockwood

M J Dillon

Affiliations

Soon will be listed here.

Abstract

Autoantibodies against components of neutrophil cytoplasm develop during adult vasculitic diseases such as Wegener's granulomatosis and microscopic polyarteritis, and they are predominantly of the IgG class. Similar but distinct antibodies have been described in children with Kawasaki disease and both IgM and IgG class antibodies are represented. This adds another clinically distinct childhood form of vasculitis to the adult forms in which autoantibodies to neutrophil cytoplasmic antigens have been detected.

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Study of the autoantibody profile after the acute phase of Kawasaki disease in a cohort of children from North India.

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