Hepatic Tuberculosis Mimicking Biliary Cystadenoma: A Radiological Dilemma

Overview

Journal Case Rep Surg

Publisher Wiley

Specialty General Surgery

Date 2015 Oct 28

PMID 26504607

Citations 4

Authors

Rajaram Sharma

Amit Kumar Dey

Kartik Mittal

Prasad Udmale

Udai Singh

Sumit Mitkar

Priya Hira

Affiliations

Soon will be listed here.

Abstract

Primary involvement of liver in tuberculosis is a rare entity. It is difficult to diagnose in absence of previous history of tuberculosis or concurrent pulmonary involvement. It is usually misdiagnosed as neoplastic liver lesion, which misdirects the treatment protocol and delays proper treatment. Here we are presenting a case of 36-year-old male patient with vague right upper quadrant abdominal pain. All the laboratory values were within normal limits. Radiological investigations were in favor of biliary cystadenoma but final diagnosis was primary focal involvement of liver in tuberculosis which was histopathologically proven to be tuberculous granulomas on biopsy of the resected mass.

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References

Chien R, Lin P, Liaw Y . Hepatic tuberculosis: comparison of miliary and local form. Infection. 1995; 23(1):5-8. DOI: 10.1007/BF01710049. View

Hersch C . TUBERCULOSIS OF THE LIVER. A STUDY OF 200 CASES. S Afr Med J. 1964; 38:857-63. View

Diaz M, Herrera T, Lopez-Vidal Y, Calva J, Hernandez R, Palacios G . Polymerase chain reaction for the detection of Mycobacterium tuberculosis DNA in tissue and assessment of its utility in the diagnosis of hepatic granulomas. J Lab Clin Med. 1996; 127(4):359-63. DOI: 10.1016/s0022-2143(96)90184-5. View

Arora R, Sharma A, Bhowate P, Bansal V, Guleria S, Dinda A . Hepatic tuberculosis mimicking Klatskin tumor: a diagnostic dilemma. Indian J Pathol Microbiol. 2008; 51(3):382-5. DOI: 10.4103/0377-4929.42517. View

Cao B, Li X, Li N, Wang Z . The nodular form of hepatic tuberculosis: contrast-enhanced ultrasonographic findings with pathologic correlation. J Ultrasound Med. 2010; 29(6):881-8. DOI: 10.7863/jum.2010.29.6.881. View

Yu R, Zhang S, Wu J, Li R . Imaging diagnosis of 12 patients with hepatic tuberculosis. World J Gastroenterol. 2004; 10(11):1639-42. PMC: 4572769. DOI: 10.3748/wjg.v10.i11.1639. View

Chong V, Lim K . Hepatobiliary tuberculosis. Singapore Med J. 2010; 51(9):744-51. View

Rab S, Beg M . Tuberculous liver abscess. Br J Clin Pract. 1977; 31(10):157-8. View

. Treatment of tuberculosis. MMWR Recomm Rep. 2003; 52(RR-11):1-77. View

10.

Huang W, Wang C, Chen W, Cheng Y, Eng H . The nodular form of hepatic tuberculosis: a review with five additional new cases. J Clin Pathol. 2003; 56(11):835-9. PMC: 1770115. DOI: 10.1136/jcp.56.11.835. View

11.

Farrokh D, Zandi B, Pezeshki Rad M, Tavakoli M . Hepatic alveolar echinococcosis. Arch Iran Med. 2015; 18(3):199-202. DOI: 0151803/AIM.0013. View

12.

Levine C . Primary macronodular hepatic tuberculosis: US and CT appearances. Gastrointest Radiol. 1990; 15(4):307-9. DOI: 10.1007/BF01888805. View

13.

Kawamori Y, Matsui O, Kitagawa K, Kadoya M, Takashima T, Yamahana T . Macronodular tuberculoma of the liver: CT and MR findings. AJR Am J Roentgenol. 1992; 158(2):311-3. DOI: 10.2214/ajr.158.2.1729789. View

14.

Fan Z, Zeng Q, Huo J, Bai L, Liu Z, Luo L . Macronodular multi-organs tuberculoma: CT and MR appearances. J Gastroenterol. 1998; 33(2):285-8. DOI: 10.1007/s005350050085. View

15.

Park J . Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases. Ann Surg Treat Res. 2015; 89(2):98-101. PMC: 4518037. DOI: 10.4174/astr.2015.89.2.98. View

16.

Oliva A, Duarte B, JONASSON O, Nadimpalli V . The nodular form of local hepatic tuberculosis. A review. J Clin Gastroenterol. 1990; 12(2):166-73. DOI: 10.1097/00004836-199004000-00011. View

17.

Alvarez S, Carpio R . Hepatobiliary tuberculosis. Dig Dis Sci. 1983; 28(3):193-200. DOI: 10.1007/BF01295113. View

18.

Vimalraj V, Jyotibasu D, Rajendran S, Ravichandran P, Jeswanth S, Balachandar T . Macronodular hepatic tuberculosis necessitating hepatic resection: a diagnostic conundrum. Can J Surg. 2007; 50(5):E7-8. PMC: 2386201. View

19.

Leeds I, Magee M, Kurbatova E, Del Rio C, Blumberg H, Leonard M . Site of extrapulmonary tuberculosis is associated with HIV infection. Clin Infect Dis. 2012; 55(1):75-81. PMC: 3493181. DOI: 10.1093/cid/cis303. View