Human Frontal-Subcortical Circuit and Asymmetric Belief Updating

Overview

Journal J Neurosci

Specialty Neurology

Date 2015 Oct 23

PMID 26490851

Citations 21

Authors

Christina Moutsiana

Caroline J Charpentier

Neil Garrett

Michael X Cohen

Tali Sharot

Affiliations

Soon will be listed here.

Abstract

Significance Statement: Beliefs of what may happen in the future are important, because they guide decisions and actions. Here, we illuminate how structural brain connectivity is related to the generation of subjective beliefs. We focus on how the valence of information is related to people's tendency to alter their beliefs. By quantifying the extent to which participants update their beliefs in response to desirable and undesirable information and relating those measures to the strength of white matter connectivity using diffusion tensor imaging, we characterize a left frontal-subcortical system that is associated simultaneously with greater belief updating in response to favorable information and reduced belief updating in response to unfavorable information. This neural architecture may allow valence to be incorporated into belief updating.

Citing Articles

Tracking politically motivated reasoning in the brain: the role of mentalizing, value-encoding, and error detection networks.

Lois G, Tsakas E, Yuen K, Riedl A Soc Cogn Affect Neurosci. 2024; 19(1).

PMID: 39167464 PMC: 11412250. DOI: 10.1093/scan/nsae056.

Within-network brain connectivity during a social optimism task is related to personal optimism and optimism for in-group members.

Moser D, Dricu M, Kotikalapudi R, Doucet G, Aue T Hum Brain Mapp. 2023; 44(12):4561-4571.

PMID: 37341428 PMC: 10365227. DOI: 10.1002/hbm.26400.

Neural dissociation between reward and salience prediction errors through the lens of optimistic bias.

Zheng Y, Mei S Hum Brain Mapp. 2023; 44(12):4545-4560.

PMID: 37334979 PMC: 10365237. DOI: 10.1002/hbm.26398.

Facilitators and barriers of preventive behaviors against COVID-19 during Ramadan: A phenomenology of Indonesian adults.

Wibowo R, Hartarto R, Bhattacharjee A, Wardani D, Sambodo N, Utomo P Front Public Health. 2023; 11:960500.

PMID: 37033074 PMC: 10073479. DOI: 10.3389/fpubh.2023.960500.

Individual differences in naturalistic learning link negative emotionality to the development of anxiety.

Villano W, Kraus N, Reneau T, Jaso B, Otto A, Heller A Sci Adv. 2023; 9(1):eadd2976.

PMID: 36598977 PMC: 9812386. DOI: 10.1126/sciadv.add2976.

References

Korn C, Sharot T, Walter H, Heekeren H, Dolan R . Depression is related to an absence of optimistically biased belief updating about future life events. Psychol Med. 2013; 44(3):579-92. PMC: 3880066. DOI: 10.1017/S0033291713001074. View

Huber R, Klucharev V, Rieskamp J . Neural correlates of informational cascades: brain mechanisms of social influence on belief updating. Soc Cogn Affect Neurosci. 2014; 10(4):589-97. PMC: 4381243. DOI: 10.1093/scan/nsu090. View

Smith S, Nichols T . Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage. 2008; 44(1):83-98. DOI: 10.1016/j.neuroimage.2008.03.061. View

Aron A, Robbins T, Poldrack R . Inhibition and the right inferior frontal cortex. Trends Cogn Sci. 2004; 8(4):170-7. DOI: 10.1016/j.tics.2004.02.010. View

Collins A, Frank M . Opponent actor learning (OpAL): modeling interactive effects of striatal dopamine on reinforcement learning and choice incentive. Psychol Rev. 2014; 121(3):337-66. DOI: 10.1037/a0037015. View

Sharot T, Kanai R, Marston D, Korn C, Rees G, Dolan R . Selectively altering belief formation in the human brain. Proc Natl Acad Sci U S A. 2012; 109(42):17058-62. PMC: 3479523. DOI: 10.1073/pnas.1205828109. View

Loewenstein G, Weber E, Hsee C, Welch N . Risk as feelings. Psychol Bull. 2001; 127(2):267-86. DOI: 10.1037/0033-2909.127.2.267. View

Sharot T, Korn C, Dolan R . How unrealistic optimism is maintained in the face of reality. Nat Neurosci. 2011; 14(11):1475-9. PMC: 3204264. DOI: 10.1038/nn.2949. View

Tekin S, Cummings J . Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update. J Psychosom Res. 2002; 53(2):647-54. DOI: 10.1016/s0022-3999(02)00428-2. View

10.

Garrett N, Sharot T . How robust is the optimistic update bias for estimating self-risk and population base rates?. PLoS One. 2014; 9(6):e98848. PMC: 4051586. DOI: 10.1371/journal.pone.0098848. View

11.

Mitchell D, Luo Q, Avny S, Kasprzycki T, Gupta K, Chen G . Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making. J Neurosci. 2009; 29(35):10827-34. PMC: 2774778. DOI: 10.1523/JNEUROSCI.0963-09.2009. View

12.

Chowdhury R, Sharot T, Wolfe T, Duzel E, Dolan R . Optimistic update bias increases in older age. Psychol Med. 2013; 44(9):2003-12. PMC: 4035755. DOI: 10.1017/S0033291713002602. View

13.

Behrens T, Woolrich M, Jenkinson M, Johansen-Berg H, Nunes R, Clare S . Characterization and propagation of uncertainty in diffusion-weighted MR imaging. Magn Reson Med. 2003; 50(5):1077-88. DOI: 10.1002/mrm.10609. View

14.

Damasio A, Grabowski T, Bechara A, Damasio H, Ponto L, Parvizi J . Subcortical and cortical brain activity during the feeling of self-generated emotions. Nat Neurosci. 2000; 3(10):1049-56. DOI: 10.1038/79871. View

15.

Li J, Delgado M, Phelps E . How instructed knowledge modulates the neural systems of reward learning. Proc Natl Acad Sci U S A. 2010; 108(1):55-60. PMC: 3017128. DOI: 10.1073/pnas.1014938108. View

16.

Kanai R, Rees G . The structural basis of inter-individual differences in human behaviour and cognition. Nat Rev Neurosci. 2011; 12(4):231-42. DOI: 10.1038/nrn3000. View

17.

LeDoux J . Brain mechanisms of emotion and emotional learning. Curr Opin Neurobiol. 1992; 2(2):191-7. DOI: 10.1016/0959-4388(92)90011-9. View

18.

Mega M, Cummings J . Frontal-subcortical circuits and neuropsychiatric disorders. J Neuropsychiatry Clin Neurosci. 1994; 6(4):358-70. DOI: 10.1176/jnp.6.4.358. View

19.

LeDoux J . The emotional brain, fear, and the amygdala. Cell Mol Neurobiol. 2003; 23(4-5):727-38. PMC: 11530156. DOI: 10.1023/a:1025048802629. View

20.

Christopoulos G, Tobler P, Bossaerts P, Dolan R, Schultz W . Neural correlates of value, risk, and risk aversion contributing to decision making under risk. J Neurosci. 2009; 29(40):12574-83. PMC: 2794196. DOI: 10.1523/JNEUROSCI.2614-09.2009. View