Treating Depressive Symptoms in Psychosis: A Network Meta-Analysis on the Effects of Non-Verbal Therapies

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2015 Oct 21

PMID 26485401

Citations 2

Authors

Laura A Steenhuis

Maaike H Nauta

Claudi L H Bocking

Gerdina H M Pijnenborg

Affiliations

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Abstract

Aims: The aim of this study was to examine whether non-verbal therapies are effective in treating depressive symptoms in psychotic disorders.

Material And Methods: A systematic literature search was performed in PubMed, Psychinfo, Picarta, Embase and ISI Web of Science, up to January 2015. Randomized controlled trials (RCTs) comparing a non-verbal intervention to a control condition in patients with psychotic disorders, whilst measuring depressive symptoms as a primary or secondary outcome, were included. The quality of studies was assessed using the 'Clinical Trials Assessment Measure for psychological treatments' (CTAM) scale. Cohen's d was calculated as a measure of effect size. Using a Network Meta-analysis, both direct and indirect evidence was investigated.

Results: 10 RCTs were included, of which three were of high quality according to the CTAM. The direct evidence demonstrated a significant effect on the reduction in depressive symptoms relative to treatment as usual (TAU), in favor of overall non-verbal therapy (ES: -0.66, 95% C.I. = -0.88, -0.44) and music therapy (ES: -0.59, 95% C.I. = -0.85, -0.33). Combining both direct and indirect evidence, yoga therapy (ES: -0.79, 95% C.I. = -1.24, -0.35) had a significant effect on depressive symptoms, and occupational therapy (ES: 1.81, 95% C.I. = 0.81, 2.81) was less effective, relative to TAU. Exercise therapy did not show a significant effect on depressive symptoms in comparison to TAU (ES: -0.02 95% C.I. = -0.67, 0.62). Due to inconsistency of study evidence, the indirect effects should be interpreted cautiously.

Conclusions: Non-verbal therapies appear to be effective in reducing depressive symptomatology in psychotic disorders, in particular music therapy and yoga therapy.

Citing Articles

Evidence for music therapy and music medicine in psychiatry: transdiagnostic meta-review of meta-analyses.

Lassner A, Siafis S, Wiese E, Leucht S, Metzner S, Wagner E BJPsych Open. 2024; 11(1):e4.

PMID: 39668615 PMC: 11733488. DOI: 10.1192/bjo.2024.826.

A scoping review of network meta-analyses assessing the efficacy and safety of complementary and alternative medicine interventions.

Pratt M, Wieland S, Ahmadzai N, Butler C, Wolfe D, Pussagoda K Syst Rev. 2020; 9(1):97.

PMID: 32354348 PMC: 7191816. DOI: 10.1186/s13643-020-01328-3.

Correction: Treating Depressive Symptoms in Psychosis: A Network Meta-Analysis on the Effects of Non-Verbal Therapies.

Steenhuis L, Nauta M, Bockting C, Pijnenborg G PLoS One. 2018; 13(12):e0209762.

PMID: 30566532 PMC: 6300325. DOI: 10.1371/journal.pone.0209762.

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