Extraordinary Cause of Acute Gastric Dilatation and Hepatic Portal Venous Gas: Chronic Use of Synthetic Cannabinoid

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2015 Oct 13

PMID 26457032

Citations 9

Authors

Mert Mahsuni Sevinc

Erdem Kinaci

Savas Bayrak

Aytul Hande Yardimci

Ekrem Cakar

Hasan Bektas

Affiliations

Soon will be listed here.

Abstract

Addiction to synthetic cannabinoids (SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation (AGD) and hepatic portal venous gas (HPVG), with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic follow-up was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG, which can be managed non-surgically despite the findings of acute abdomen.

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References

Allen J, de Moore G, Heddle R, Twartz J . Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. Gut. 2004; 53(11):1566-70. PMC: 1774264. DOI: 10.1136/gut.2003.036350. View

Allaparthi S, Anand C . Acute gastric dilatation: a transient cause of hepatic portal venous gas-case report and review of the literature. Case Rep Gastrointest Med. 2013; 2013:723160. PMC: 3683454. DOI: 10.1155/2013/723160. View

Turan M, Sen M, Canbay E, Karadayi K, Yildiz E . Gastric necrosis and perforation caused by acute gastric dilatation: report of a case. Surg Today. 2003; 33(4):302-4. DOI: 10.1007/s005950300068. View

Partosoedarso E, Abrahams T, Scullion R, Moerschbaecher J, Hornby P . Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets. J Physiol. 2003; 550(Pt 1):149-58. PMC: 2343023. DOI: 10.1113/jphysiol.2003.042242. View

Abboud B, El Hachem J, Yazbeck T, Doumit C . Hepatic portal venous gas: physiopathology, etiology, prognosis and treatment. World J Gastroenterol. 2009; 15(29):3585-90. PMC: 2721230. DOI: 10.3748/wjg.15.3585. View

Oomatia A, Carroll N, Safranek P . Acute gastric necrosis and air in the hepatic-portal vein secondary to a strangulated paraumbilical hernia. Lancet. 2013; 382(9906):1733. DOI: 10.1016/S0140-6736(12)61778-4. View

Krowicki Z, Moerschbaecher J, Winsauer P, Digavalli S, Hornby P . Delta9-tetrahydrocannabinol inhibits gastric motility in the rat through cannabinoid CB1 receptors. Eur J Pharmacol. 1999; 371(2-3):187-96. DOI: 10.1016/s0014-2999(99)00165-x. View

Choung R, Locke 3rd G, Lee R, Schleck C, Zinsmeister A, Talley N . Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. Neurogastroenterol Motil. 2011; 24(1):20-6, e1. PMC: 3375678. DOI: 10.1111/j.1365-2982.2011.01791.x. View

Gurdal F, Asirdizer M, Aker R, Korkut S, Gocer Y, Kucukibrahimoglu E . Review of detection frequency and type of synthetic cannabinoids in herbal compounds analyzed by Istanbul Narcotic Department of the Council of Forensic Medicine, Turkey. J Forensic Leg Med. 2013; 20(6):667-72. DOI: 10.1016/j.jflm.2013.03.041. View

10.

Tramer M, Carroll D, Campbell F, Reynolds D, Moore R, McQuay H . Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review. BMJ. 2001; 323(7303):16-21. PMC: 34325. DOI: 10.1136/bmj.323.7303.16. View

11.

Pertwee R . Cannabinoids and the gastrointestinal tract. Gut. 2001; 48(6):859-67. PMC: 1728337. DOI: 10.1136/gut.48.6.859. View

12.

Koklu E, Yuksel I, Bayar N, Ureyen C, Arslan S . A new cause of silent myocardial infarction: Bonsai. Anatol J Cardiol. 2015; 15(1):69-70. PMC: 5336902. DOI: 10.5152/akd.2014.5870. View

13.

Benson M . Adult survival with intrahepatic portal venous gas secondary to acute gastric dilatation, with a review of portal venous gas. Clin Radiol. 1985; 36(4):441-3. DOI: 10.1016/s0009-9260(85)80339-1. View

14.

Nelson A, Millington T, Sahani D, Chung R, Bauer C, Hertl M . Hepatic portal venous gas: the ABCs of management. Arch Surg. 2009; 144(6):575-81. DOI: 10.1001/archsurg.2009.88. View

15.

Kinoshita H, Shinozaki M, Tanimura H, Umemoto Y, Sakaguchi S, Takifuji K . Clinical features and management of hepatic portal venous gas: four case reports and cumulative review of the literature. Arch Surg. 2001; 136(12):1410-4. DOI: 10.1001/archsurg.136.12.1410. View

16.

Kogan N, Mechoulam R . Cannabinoids in health and disease. Dialogues Clin Neurosci. 2008; 9(4):413-30. PMC: 3202504. View

17.

Izzo A, Mascolo N, Capasso R, Germano M, De Pasquale R, Capasso F . Inhibitory effect of cannabinoid agonists on gastric emptying in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1999; 360(2):221-3. DOI: 10.1007/s002109900054. View

18.

Lim J, Duke G, Eachempati S . Superior mesenteric artery syndrome presenting with acute massive gastric dilatation, gastric wall pneumatosis, and portal venous gas. Surgery. 2003; 134(5):840-3. DOI: 10.1016/s0039-6060(02)21677-3. View

19.

Sontineni S, Chaudhary S, Sontineni V, Lanspa S . Cannabinoid hyperemesis syndrome: clinical diagnosis of an underrecognised manifestation of chronic cannabis abuse. World J Gastroenterol. 2009; 15(10):1264-6. PMC: 2658859. DOI: 10.3748/wjg.15.1264. View

20.

Radin D, Rosen R, Halls J . Acute gastric dilatation: a rare cause of portal venous gas. AJR Am J Roentgenol. 1987; 148(2):279-80. DOI: 10.2214/ajr.148.2.279. View