Management of Previously Treated Tuberculosis Patients in Kalutara District, Sri Lanka: How Are We Faring?

Overview

Journal Public Health Action

Date 2015 Sep 25

PMID 26399208

Citations 13

Authors

S C Abeygunawardena

B N Sharath

R Van den Bergh

B Naik

N Pallewatte

M N N Masaima

Affiliations

Soon will be listed here.

Abstract

Setting: District Chest Clinic, Kalutara, Sri Lanka.

Objectives: To determine the coverage of culture and drug susceptibility testing (CDST), delays in CDST, treatment initiation, obtaining CDST results and treatment outcomes of previously treated tuberculosis (TB) patients.

Design: Retrospective cohort study involving review of records and reports. All previously treated TB patients from January 2008 to June 2013 were included in the study.

Results: Of 160 patients, 126 (79%) samples were sent for CDST; 79 (63%) were culture-positive and no multi-drug-resistant (MDR) TB cases were reported. Respectively 9% and 15% of patients experienced a delay in sending samples (median delay 21 days) and receiving CDST reports (median delay 71 days), while 20% experienced delays in initiating the retreatment regimen (median delay 11.5 days). The cohort recorded an 82% treatment success rate.

Conclusion: Of all retreatment patients, only 79% were tested for CDST and there were sizeable delays in sample transportation and treatment initiation. Possible ways forward to strengthen the programme are discussed.

Citing Articles

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Attrition and delays before treatment initiation among patients with MDR-TB in China (2006-13): Magnitude and risk factors.

Xu C, Li R, Shewade H, Jeyashree K, Ruan Y, Zhang C PLoS One. 2019; 14(4):e0214943.

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A systematic review of clinical outcomes on the WHO Category II retreatment regimen for tuberculosis.

Cohen D, Meghji J, Squire S Int J Tuberc Lung Dis. 2018; 22(10):1127-1134.

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Delay and attrition before treatment initiation among MDR-TB patients in five districts of Gujarat, India.

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Provider reported barriers and solutions to improve testing among tuberculosis patients 'eligible for drug susceptibility test': A qualitative study from programmatic setting in India.

Shewade H, Kokane A, Singh A, Parmar M, Verma M, Desikan P PLoS One. 2018; 13(4):e0196162.

PMID: 29677210 PMC: 5909888. DOI: 10.1371/journal.pone.0196162.

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