Molecular Cross-Talk at the Feto-Maternal Interface

Overview

Journal Cold Spring Harb Perspect Med

Specialty General Medicine

Date 2015 Sep 20

PMID 26385089

Citations 38

Authors

Gendie E Lash

Affiliations

Soon will be listed here.

Abstract

Molecular cross-talk at the feto-maternal interface occurs between many different cell types, including uterine leukocytes, extravillous trophoblast cells, and uterine spiral arteries, is essential for the establishment and maintenance of pregnancy. This review concentrates on human pregnancy and examines three main areas in which cross-talk occurs; immune tolerance, regulation of extravillous trophoblast invasion, and remodeling of the uterine spiral arteries.

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References

Akbari O, DeKruyff R, Umetsu D . Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol. 2001; 2(8):725-31. DOI: 10.1038/90667. View

Irving J, Lysiak J, Graham C, Hearn S, Han V, Lala P . Characteristics of trophoblast cells migrating from first trimester chorionic villus explants and propagated in culture. Placenta. 1995; 16(5):413-33. DOI: 10.1016/0143-4004(95)90100-0. View

Huber A, Saleh L, Bauer S, Husslein P, Knofler M . TNFalpha-mediated induction of PAI-1 restricts invasion of HTR-8/SVneo trophoblast cells. Placenta. 2005; 27(2-3):127-36. DOI: 10.1016/j.placenta.2005.02.012. View

Oki N, Matsuo H, Nakago S, Murakoshi H, Laoag-Fernandez J, Maruo T . Effects of 3,5,3'-triiodothyronine on the invasive potential and the expression of integrins and matrix metalloproteinases in cultured early placental extravillous trophoblasts. J Clin Endocrinol Metab. 2004; 89(10):5213-21. DOI: 10.1210/jc.2004-0352. View

Champion H, Innes B, Robson S, Lash G, Bulmer J . Effects of interleukin-6 on extravillous trophoblast invasion in early human pregnancy. Mol Hum Reprod. 2012; 18(8):391-400. DOI: 10.1093/molehr/gas010. View

Gustafsson C, Mjosberg J, Matussek A, Geffers R, Matthiesen L, Berg G . Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype. PLoS One. 2008; 3(4):e2078. PMC: 2323105. DOI: 10.1371/journal.pone.0002078. View

Fest S, Aldo P, Abrahams V, Visintin I, Alvero A, Chen R . Trophoblast-macrophage interactions: a regulatory network for the protection of pregnancy. Am J Reprod Immunol. 2006; 57(1):55-66. DOI: 10.1111/j.1600-0897.2006.00446.x. View

Yamamoto-Tabata T, McDonagh S, Chang H, Fisher S, Pereira L . Human cytomegalovirus interleukin-10 downregulates metalloproteinase activity and impairs endothelial cell migration and placental cytotrophoblast invasiveness in vitro. J Virol. 2004; 78(6):2831-40. PMC: 353759. DOI: 10.1128/jvi.78.6.2831-2840.2004. View

Irving J, Lala P . Functional role of cell surface integrins on human trophoblast cell migration: regulation by TGF-beta, IGF-II, and IGFBP-1. Exp Cell Res. 1995; 217(2):419-27. DOI: 10.1006/excr.1995.1105. View

10.

Martinez F, Helming L, Gordon S . Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol. 2008; 27:451-83. DOI: 10.1146/annurev.immunol.021908.132532. View

11.

Juretic K, Strbo N, Bogovic Crncic T, Laskarin G, Rukavina D . An insight into the dendritic cells at the maternal-fetal interface. Am J Reprod Immunol. 2005; 52(6):350-5. DOI: 10.1111/j.1600-0897.2004.00232.x. View

12.

Jokhi P, King A, Loke Y . Production of granulocyte-macrophage colony-stimulating factor by human trophoblast cells and by decidual large granular lymphocytes. Hum Reprod. 1994; 9(9):1660-9. DOI: 10.1093/oxfordjournals.humrep.a138769. View

13.

Bengtsson A, Ryan E, Giordano D, Magaletti D, Clark E . 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells. Blood. 2004; 104(5):1404-10. DOI: 10.1182/blood-2003-10-3380. View

14.

Nishioka Y, Higuchi T, Sato Y, Yoshioka S, Tatsumi K, Fujiwara H . Human migrating extravillous trophoblasts express a cell surface peptidase, carboxypeptidase-M. Mol Hum Reprod. 2003; 9(12):799-806. DOI: 10.1093/molehr/gag092. View

15.

Frank H, Morrish D, Potgens A, Genbacev O, Kumpel B, Caniggia I . Cell culture models of human trophoblast: primary culture of trophoblast--a workshop report. Placenta. 2001; 22 Suppl A:S107-9. DOI: 10.1053/plac.2001.0644. View

16.

Pongcharoen S, Niumsup P, Sanguansermsri D, Supalap K, Butkhamchot P . The effect of interleukin-17 on the proliferation and invasion of JEG-3 human choriocarcinoma cells. Am J Reprod Immunol. 2006; 55(4):291-300. DOI: 10.1111/j.1600-0897.2006.00366.x. View

17.

Norwitz E, Schust D, Fisher S . Implantation and the survival of early pregnancy. N Engl J Med. 2002; 345(19):1400-8. DOI: 10.1056/NEJMra000763. View

18.

Riboldi E, Musso T, Moroni E, Urbinati C, Bernasconi S, Rusnati M . Cutting edge: proangiogenic properties of alternatively activated dendritic cells. J Immunol. 2005; 175(5):2788-92. DOI: 10.4049/jimmunol.175.5.2788. View

19.

Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S . Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med. 2006; 12(9):1065-74. DOI: 10.1038/nm1452. View

20.

Otun H, Lash G, Innes B, Bulmer J, Naruse K, Hannon T . Effect of tumour necrosis factor-α in combination with interferon-γ on first trimester extravillous trophoblast invasion. J Reprod Immunol. 2010; 88(1):1-11. DOI: 10.1016/j.jri.2010.10.003. View