Non-Proteinuric Diabetic Nephropathy

Overview

Journal J Clin Med

Specialty General Medicine

Date 2015 Sep 16

PMID 26371050

Citations 24

Authors

Nicolas Roberto Robles

Juan Villa

Roman Hernandez Gallego

Affiliations

Soon will be listed here.

Abstract

Diabetic nephropathy patients traditionally show significant macroalbuminuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. Epidemiological surveys confirm that chronic kidney disease (CKD) diagnosed by a low glomerular filtration rate (GFR) is more common in diabetic patients than in the non-diabetic population but a low number of patients had levels of proteinuria above that which traditionally defines overt diabetic nephropathy (>500 mg/g). The large number of patients with low levels of proteinuria suggests that the traditional clinical paradigm of overt diabetic nephropathy is changing since it does not seem to be the underlying renal lesion in most of diabetic subjects with CKD.

Citing Articles

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