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Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls

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Journal PLoS One
Date 2015 Sep 15
PMID 26366721
Citations 13
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Abstract

Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples.

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