Pre- and Postmortem Imaging of Transplanted Cells

Overview

Journal Int J Nanomedicine

Publisher Dove Medical Press

Specialty Biotechnology

Date 2015 Sep 15

PMID 26366076

Citations 8

Authors

Anna Andrzejewska

Adam Nowakowski

Miroslaw Janowski

Jeff W M Bulte

Assaf A Gilad

Piotr Walczak

Barbara Lukomska

Affiliations

Soon will be listed here.

Abstract

Therapeutic interventions based on the transplantation of stem and progenitor cells have garnered increasing interest. This interest is fueled by successful preclinical studies for indications in many diseases, including the cardiovascular, central nervous, and musculoskeletal system. Further progress in this field is contingent upon access to techniques that facilitate an unambiguous identification and characterization of grafted cells. Such methods are invaluable for optimization of cell delivery, improvement of cell survival, and assessment of the functional integration of grafted cells. Following is a focused overview of the currently available cell detection and tracking methodologies that covers the entire spectrum from pre- to postmortem cell identification.

Citing Articles

Cadaveric Stem Cells: Their Research Potential and Limitations.

Ciesla J, Tomsia M Front Genet. 2022; 12:798161.

PMID: 35003228 PMC: 8727551. DOI: 10.3389/fgene.2021.798161.

Mesenchymal Stem Cells Do Not Lose Direct Labels Including Iron Oxide Nanoparticles and DFO-Zr Chelates through Secretion of Extracellular Vesicles.

Gao Y, Jablonska A, Chu C, Walczak P, Janowski M Membranes (Basel). 2021; 11(7).

PMID: 34209565 PMC: 8305565. DOI: 10.3390/membranes11070484.

Mesenchymal Stem Cells for Neurological Disorders.

Andrzejewska A, Dabrowska S, Lukomska B, Janowski M Adv Sci (Weinh). 2021; 8(7):2002944.

PMID: 33854883 PMC: 8024997. DOI: 10.1002/advs.202002944.

Comparative strategies for stem cell biodistribution in a preclinical study.

Wang F, Wang Z, Wang F, Dong K, Zhang J, Sun Y Acta Pharmacol Sin. 2019; 41(4):572-580.

PMID: 31705124 PMC: 7470780. DOI: 10.1038/s41401-019-0313-x.

Labeling of human mesenchymal stem cells with different classes of vital stains: robustness and toxicity.

Andrzejewska A, Jablonska A, Seta M, Dabrowska S, Walczak P, Janowski M Stem Cell Res Ther. 2019; 10(1):187.

PMID: 31238982 PMC: 6593614. DOI: 10.1186/s13287-019-1296-8.

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