Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application

Overview

Journal J Drugs Dermatol

Specialty Dermatology

Date 2015 Sep 11

PMID 26355614

Citations 25

Authors

Brian C Schulte

Wesley Wu

Ted Rosen

Affiliations

Soon will be listed here.

Abstract

Azelaic acid is a complex molecule with many diverse activities. The latter include anti-infective and anti-inflammatory action. The agent also inhibits follicular keratinization and epidermal melanogenesis. Due to the wide variety of biological activities, azelaic acid has been utilized as a management tool in a broad spectrum of disease states and cutaneous disorders. This paper reviews the clinical utility of azelaic acid, noting the quality of the evidence supporting each potential use.

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