The Impact of Coronary Artery Disease Severity on Late Survival After Combined Aortic Valve Replacement and Coronary Artery Bypass Grafting - Experience of a Single Cardiac Surgery Center

Overview

Journal Kardiochir Torakochirurgia Pol

Publisher Termedia

Date 2015 Sep 4

PMID 26336450

Citations 5

Authors

Bartlomiej Perek

Marcin Misterski

Wojciech Stachowiak

Piotr Buczkowski

Sebastian Stefaniak

Mateusz Puslecki

Tomasz Urbanowicz

Wiktor Budniak

Marek Jemielity

Affiliations

Soon will be listed here.

Abstract

Introduction: The severity of coronary artery disease (CAD) may have an impact on the outcomes of patients (pts) after aortic valve replacement (AVR) and coronary artery bypass grafting (CABG).

Aim: The aim of the study was to analyze survival after simultaneous AVR and CABG with respect to CAD severity.

Material And Methods: The study involved 143 consecutive pts (40 women and 103 men) with a mean age of 65.1 ± 7.7 years treated between 2006 and 2009. The indication for surgery was aortic stenosis accompanied by left main or three-vessel disease (group A; n = 43) and by single- or two-vessel disease (group B; n = 100). In-hospital and late mortality were analyzed. Post-discharge survival was estimated using the Kaplan-Meier method. Moreover, selected preoperative clinical and echocardiographic data as well as intraoperative variables were compared between the groups.

Results: In-hospital mortality was 4.7% in group A and 3.0% in group B (NS). The 12-month and 48-month survival probability rates were 0.88 ± 0.05 and 0.83 ± 0.06 in group A, and 0.97 ± 0.01 and 0.92 ± 0.03 in group B, respectively (p < 0.05). Patients in group A and B differed (p < 0.05) with respect to the preoperative prevalence of arterial hypertension (65.1% vs. 42.0%) and atrial fibrillation (18.6% vs. 6.0%) as well as with regard to the rate of complete revascularization (20.9% vs. 85.0%, group A and B, respectively).

Conclusions: Coronary artery disease severity impacts long-term survival after combined AVR and CABG. Patients with left main or three-vessel disease more often undergo incomplete surgical revascularization, and this fact may be one of the predictors of an unfavorable outcome.

Citing Articles

Pre-operative systemic inflammatory response index influences long-term survival rate in off-pump surgical revascularization.

Urbanowicz T, Olasinska-Wisniewska A, Michalak M, Perek B, Al-Imam A, Rodzki M PLoS One. 2022; 17(12):e0276138.

PMID: 36520919 PMC: 9754600. DOI: 10.1371/journal.pone.0276138.

The Significance of Systemic Immune-Inflammatory Index for Mortality Prediction in Diabetic Patients Treated with Off-Pump Coronary Artery Bypass Surgery.

Urbanowicz T, Michalak M, Al-Imam A, Olasinska-Wisniewska A, Rodzki M, Witkowska A Diagnostics (Basel). 2022; 12(3).

PMID: 35328187 PMC: 8947274. DOI: 10.3390/diagnostics12030634.

Platelet-Leucocyte Aggregates as Novel Biomarkers in Cardiovascular Diseases.

Pluta K, Porebska K, Urbanowicz T, Gasecka A, Olasinska-Wisniewska A, Targonski R Biology (Basel). 2022; 11(2).

PMID: 35205091 PMC: 8869671. DOI: 10.3390/biology11020224.

How the COVID-19 pandemic changed treatment of severe aortic stenosis: a single cardiac center experience.

Perek B, Olasinska-Wisniewska A, Misterski M, Puslecki M, Grygier M, Buczkowski P J Thorac Dis. 2021; 13(2):906-917.

PMID: 33717563 PMC: 7947507. DOI: 10.21037/jtd-20-3025.

Late subclinical hemolysis and long-term outcomes after aortic valve replacement with On-X mechanical prostheses - a preliminary single-center report.

Perek B, Slawek S, Malinska A, Katynska I, Puslecki M, Szymak-Pawelczyk B Kardiochir Torakochirurgia Pol. 2017; 14(3):175-179.

PMID: 29181045 PMC: 5701593. DOI: 10.5114/kitp.2017.70531.

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