Epigenetic Reprogramming in Solid Tumors: Therapeutic Implications of EZH2 Gain-of-function Mutations
Overview
Affiliations
-mediated H3K27me3 is a predictive biomarker and therapeutic target in uveal melanoma.
Hou C, Xiao L, Ren X, Cheng L, Guo B, Zhang M Front Genet. 2022; 13:1013475.
PMID: 36276954 PMC: 9582331. DOI: 10.3389/fgene.2022.1013475.
Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications.
Vanni I, Tanda E, Dalmasso B, Pastorino L, Andreotti V, Bruno W Front Mol Biosci. 2020; 7:172.
PMID: 32850962 PMC: 7396525. DOI: 10.3389/fmolb.2020.00172.
Orchestration of H3K27 methylation: mechanisms and therapeutic implication.
Pan M, Hsu M, Chen L, Hung W Cell Mol Life Sci. 2017; 75(2):209-223.
PMID: 28717873 PMC: 5756243. DOI: 10.1007/s00018-017-2596-8.