Preventing Heart Failure in Inflammatory and Immune Disorders

Overview

Journal Curr Cardiovasc Risk Rep

Publisher Springer

Specialty Cardiology & Vascular Diseases

Date 2015 Aug 29

PMID 26316924

Citations 3

Authors

Maya Serhal

Chris T Longenecker

Affiliations

Soon will be listed here.

Abstract

Patients with chronic inflammatory diseases are at increased risk for heart failure due to ischemic heart disease and other causes including heart failure with preserved ejection fraction. Using rheumatoid arthritis and treated HIV infection as two prototypical examples, we review the epidemiology and potential therapies to prevent heart failure in these populations. Particular focus is given to anti-inflammatory therapies including statins and biologic disease modifying drugs. There is also limited evidence for lifestyle changes and blockade of the renin-angiotensin-aldosterone system. We conclude by proposing how a strategy for heart failure prevention, such as the model tested in the Screening To Prevent Heart Failure (STOP-HF) trial, may be adapted to chronic inflammatory disease.

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