Ligand-Enabled Meta-C-H Alkylation and Arylation Using a Modified Norbornene

Overview

Journal J Am Chem Soc

Publisher American Chemical Society

Specialty Chemistry

Date 2015 Aug 28

PMID 26313012

Citations 42

Authors

Peng-Xiang Shen

Xiao-Chen Wang

Peng Wang

Ru-Yi Zhu

Jin-Quan Yu

Affiliations

Soon will be listed here.

Abstract

2-Carbomethoxynorbornene is identified as a more effective transient mediator to promote a Pd(II)-catalyzed meta-C(sp(2))-H alkylation of amides with various alkyl iodides as well as arylation with previously incompatible aryl iodides. The use of a tailor-made quinoline ligand is also crucial for this reaction to proceed.

Citing Articles

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