» Articles » PMID: 26308602

Imaging of Prehospital Stroke Therapeutics

Overview
Date 2015 Aug 27
PMID 26308602
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Despite significant quality improvement efforts to streamline in-hospital acute stroke care in the conventional model, there remain inherent layers of treatment delays, which could be eliminated with prehospital diagnostics and therapeutics administered in a mobile stroke unit. Early diagnosis using telestroke and neuroimaging while in the ambulance may enable targeted routing to hospitals with specialized care, which will likely improve patient outcomes. Key clinical trials in telestroke, mobile stroke units with prehospital neuroimaging capability, prehospital ultrasound and co-administration of various classes of neuroprotectives, antiplatelets and antithrombin agents with intravenous thrombolysis are discussed in this article.

Citing Articles

Prehospital identification of intracerebral haemorrhage: a scoping review of early clinical features and portable devices.

Almubayyidh M, Alghamdi I, Parry-Jones A, Jenkins D BMJ Open. 2024; 14(4):e079316.

PMID: 38643005 PMC: 11033659. DOI: 10.1136/bmjopen-2023-079316.


How to Improve the Management of Acute Ischemic Stroke by Modern Technologies, Artificial Intelligence, and New Treatment Methods.

Zelenak K, Krajina A, Meyer L, Fiehler J, Esmint Artificial Intelligence And Robotics Ad Hoc Committee , Behme D Life (Basel). 2021; 11(6).

PMID: 34072071 PMC: 8229281. DOI: 10.3390/life11060488.


A scoping review of pre-hospital technology to assist ambulance personnel with patient diagnosis or stratification during the emergency assessment of suspected stroke.

Lumley H, Flynn D, Shaw L, McClelland G, Ford G, White P BMC Emerg Med. 2020; 20(1):30.

PMID: 32336270 PMC: 7183583. DOI: 10.1186/s12873-020-00323-0.


miR-130a alleviates neuronal apoptosis and changes in expression of Bcl-2/Bax and caspase-3 in cerebral infarction rats through PTEN/PI3K/Akt signaling pathway.

Wang Y, Gu J, Hu L, Kong L, Wang T, Di M Exp Ther Med. 2020; 19(3):2119-2126.

PMID: 32104274 PMC: 7027342. DOI: 10.3892/etm.2020.8415.


Telestroke.

Dumitrascu O, Demaerschalk B Curr Cardiol Rep. 2017; 19(9):85.

PMID: 28785990 DOI: 10.1007/s11886-017-0895-1.

References
1.
Levine S, Gorman M . "Telestroke" : the application of telemedicine for stroke. Stroke. 1999; 30(2):464-9. DOI: 10.1161/01.str.30.2.464. View

2.
Switzer J, Demaerschalk B, Xie J, Fan L, Villa K, Wu E . Cost-effectiveness of hub-and-spoke telestroke networks for the management of acute ischemic stroke from the hospitals' perspectives. Circ Cardiovasc Qual Outcomes. 2012; 6(1):18-26. DOI: 10.1161/CIRCOUTCOMES.112.967125. View

3.
Schumacher H, Bateman B, Boden-Albala B, Berman M, Mohr J, Sacco R . Use of thrombolysis in acute ischemic stroke: analysis of the Nationwide Inpatient Sample 1999 to 2004. Ann Emerg Med. 2007; 50(2):99-107. DOI: 10.1016/j.annemergmed.2007.01.021. View

4.
Llanes J, Kidwell C, Starkman S, Leary M, Eckstein M, Saver J . The Los Angeles Motor Scale (LAMS): a new measure to characterize stroke severity in the field. Prehosp Emerg Care. 2003; 8(1):46-50. DOI: 10.1080/312703002806. View

5.
Schwamm L, Rosenthal E, Hirshberg A, Schaefer P, Little E, Kvedar J . Virtual TeleStroke support for the emergency department evaluation of acute stroke. Acad Emerg Med. 2004; 11(11):1193-7. DOI: 10.1197/j.aem.2004.08.014. View