» Articles » PMID: 26291628

Self-Reported Traumatic Brain Injury, Health and Rate of Chronic Multisymptom Illness in Veterans From the 1990-1991 Gulf War

Overview
Date 2015 Aug 21
PMID 26291628
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Traumatic brain injury (TBI) was not considered to be common in the 1990-1991 Gulf War (GW). Therefore, the relationship between TBI and chronic health symptoms experienced by GW veterans is unknown. Health symptoms reported by veterans deployed more recently to this region (Operations Enduring and Iraqi Freedom) are similar to those of GW veterans and have been primarily attributed to TBI.

Objective: To examine the relationships among self-reported TBI, health symptoms, chronic multisymptom illness (CMI), and health-related quality of life among GW veterans.

Participants: Participants included 1 274 GW veterans from the Devens Cohort Study, 156 of whom self-reported a history of TBI (12.2% of the sample).

Design: Cross-sectional retrospective analysis of existing survey data.

Main Measures: A 52-item health symptom checklist and the RAND 36-Item Health short Form Survey.

Results: Self-reported TBI in GW Veterans is related to increased rates of health symptoms, CMI, and poorer health-related quality of life.

Conclusions: Gulf War veterans' self-reported exposure to TBI is related to increased rates of chronic health symptoms and CMI, which interfere with everyday activities of daily living.

Citing Articles

Impact of gulf war toxic exposures after mild traumatic brain injury.

Ferguson S, McCartan R, Browning M, Hahn-Townsend C, Gratkowski A, Morin A Acta Neuropathol Commun. 2022; 10(1):147.

PMID: 36258255 PMC: 9580120. DOI: 10.1186/s40478-022-01449-x.


A randomized phase II remote study to assess Bacopa for Gulf War Illness associated cognitive dysfunction: Design and methods of a national study.

Cheema A, Wiener L, McNeil R, Abreu M, Craddock T, Fletcher M Life Sci. 2021; 282:119819.

PMID: 34256038 PMC: 9189930. DOI: 10.1016/j.lfs.2021.119819.


Sex-Based Differences in Plasma Autoantibodies to Central Nervous System Proteins in Gulf War Veterans versus Healthy and Symptomatic Controls.

Abou-Donia M, Krengel M, Lapadula E, Zundel C, LeClair J, Massaro J Brain Sci. 2021; 11(2).

PMID: 33498629 PMC: 7911379. DOI: 10.3390/brainsci11020148.


Neuroimaging Markers for Studying Gulf-War Illness: Single-Subject Level Analytical Method Based on Machine Learning.

Guan Y, Cheng C, Chen W, Zhang Y, Koo S, Krengel M Brain Sci. 2020; 10(11).

PMID: 33233672 PMC: 7699718. DOI: 10.3390/brainsci10110884.


The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans.

Chao L Int J Environ Res Public Health. 2020; 17(19).

PMID: 33007845 PMC: 7579246. DOI: 10.3390/ijerph17197158.