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Meniscal Transplantation: Still Experimental Surgery? A Review

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Specialty Orthopedics
Date 2015 Aug 18
PMID 26280615
Citations 5
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Abstract

Introduction: The objective of this review is to give a state of affairs of meniscal transplantation, with the accent on preservation and surgical techniques.

Materials And Methods: All articles were selected by performing a search on the literature by using relevant keywords. The most relevant articles were selected with close attention to the publication date.

Results: When a meniscal tear is diagnosed, suture can be an option in the vascular zone, whereas the more frequently affected avascular zone heals poorly. A meniscectomy however is not without consequences, wherefore meniscal transplantation can be seen as a therapeutic option for pain reduction and improvement of function when the meniscus is lost. The meniscal scaffold, allograft and autograft can be currently withheld as possible grafts, where the meniscal scaffolds hold great promise as an alternative to the allograft. Various fixation techniques are therefore developed, where viable, deep frozen as well as cryopreservated allografts seem to give the most promising short term results. The transplantation can be performed using an open as well as an arthroscopic technique, using soft tissue fixation, bone plugs or blocks. De primacy of one technique can't be proven. In general meniscal transplantation can be considered as an acceptable procedure.

Discussion: Since the outcomes of different studies are difficult to compare, an attempt should be made to limit new studies to the comparison of one aspect. We can conclude that larger, more comparative randomised controlled long-term studies are necessary to resolve which techniques can give the best long-term results.

Citing Articles

Influence of peracetic acid-ethanol sterilisation on the biomechanical properties of human meniscus transplants.

Eras V, Graffunder J, Ahmed N, Brune J J Exp Orthop. 2021; 8(1):18.

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Higher survivorship following meniscal allograft transplantation in less worn knees justifies earlier referral for symptomatic patients: experience from 240 patients.

Bloch B, Asplin L, Smith N, Thompson P, Spalding T Knee Surg Sports Traumatol Arthrosc. 2019; 27(6):1891-1899.

PMID: 30900033 DOI: 10.1007/s00167-019-05459-6.


Modern treatment of meniscal tears.

Doral M, Bilge O, Huri G, Turhan E, Verdonk R EFORT Open Rev. 2018; 3(5):260-268.

PMID: 29951265 PMC: 5994634. DOI: 10.1302/2058-5241.3.170067.


Arthroscopic Lateral Meniscal Allograft Transplantation With the Key-Hole Technique.

Lee D, Park J, Chung K, Ha J, Kim J Arthrosc Tech. 2018; 6(5):e1815-e1820.

PMID: 29430389 PMC: 5799489. DOI: 10.1016/j.eats.2017.06.057.


Meniscal Allograft Transplantation Does Not Prevent or Delay Progression of Knee Osteoarthritis.

Van Der Straeten C, Byttebier P, Eeckhoudt A, Victor J PLoS One. 2016; 11(5):e0156183.

PMID: 27228174 PMC: 4881946. DOI: 10.1371/journal.pone.0156183.