Histoplasmosis Infections Worldwide: Thinking Outside of the Ohio River Valley

Overview

Journal Curr Trop Med Rep

Specialty Tropical Medicine

Date 2015 Aug 18

PMID 26279969

Citations 99

Authors

Nathan C Bahr

Spinello Antinori

L Joseph Wheat

George A Sarosi

Affiliations

Soon will be listed here.

Abstract

In the United States, histoplasmosis is generally thought to occur mainly in the Ohio and Mississippi River Valleys, and the classic map of histoplasmosis distribution reflecting this is second nature to many U.S. physicians. With the advent of the HIV pandemic reports of patients with progressive disseminated histoplasmosis and AIDS came from regions of known endemicity, as well as from regions not thought to be endemic for histoplasmosis throughout the world. In addition, our expanding armamentarium of immunosuppressive medications and biologics has increased the diagnosis of histoplasmosis worldwide. While our knowledge of areas in which histoplasmosis is endemic has improved, it is still incomplete. Our contention is that physicians should consider with the right constellations of symptoms in any febrile patient with immune suppression, regardless of geographic location or travel history.

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