Transrectal-ultrasound Prostatic Biopsy Preparation: Rectal Enema Vs. Mechanical Bowel Preparation

Overview

Journal Cent European J Urol

Specialty Urology

Date 2015 Aug 8

PMID 26251750

Citations 4

Authors

Cosimo De Nunzio

Riccardo Lombardo

Fabrizio Presicce

Mariangela Bellangino

Enrico Finazzi Agro

Matteo Bonetto Gambrosier

Alberto Trucchi

Stefano Petta

Andrea Tubaro

Affiliations

Soon will be listed here.

Abstract

Introduction: Transrectal prostate biopsy (TRUSbx) is the standard for the diagnosis of prostate cancer. Different bowel preparations are used for patients undergoing TRUSbx. The aim of our study was to compare two different bowel preparations for TRUSbx.

Material And Methods: From May 2012 and onwards, a selected group of men undergoing TRUS 12-core prostate biopsy were enrolled into a prospective database. Patients were randomized 1:1 to receive a rectal enema (Group A) the night before the procedure or polyethylene glycol 34.8 grams/4 liters of water the day before the procedure (Group B). A VAS scale to evaluate the patients' discomfort according to the two preparations was collected. The same antibiotic prophylaxis was performed in both groups. All complications were prospectively recorded and graded according to the Clavien Classification System (CCS).

Results: A total of 198 patients were consecutively enrolled. Mean age was 67.5 ±7.9 years, mean body mass index (BMI) was 27.1 ±4.2 Kg/m(2), mean PSA value was 9.3 ±12.6 ng/ml and the mean prostatic volume was 60.6 ±29 ml. 97 patients were enrolled in Group A and 101 in Group B. Overall post-biopsy morbidity rate was 60%. No significant differences for low-grade and high-grade complications was observed between the two groups. Patients receiving the rectal enema presented with a significantly lower VAS score (3.1 ±1.1 vs. 5.9 ±1.7; p = 0.02).

Conclusions: Our study confirmed that a rectal enema should be considered as the standard bowel preparation in patients undergoing a TRUS biopsy; it is as effective as PEG and associated with less discomfort.

Citing Articles

Role of Perilesional Sampling of Patients Undergoing Fusion Prostate Biopsies.

Lombardo R, Tema G, Nacchia A, Mancini E, Franco S, Zammitti F Life (Basel). 2023; 13(8).

PMID: 37629576 PMC: 10455324. DOI: 10.3390/life13081719.

[Prostate biopsy-infection prophylaxis and patient preparation].

Pilatz A, Alidjanov J, Bonkat G, Wagenlehner F Urologie. 2023; 62(5):459-463.

PMID: 36882551 DOI: 10.1007/s00120-023-02065-w.

Guidelines for Transrectal Ultrasonography-Guided Prostate Biopsy: Korean Society of Urogenital Radiology Consensus Statement for Patient Preparation, Standard Technique, and Biopsy-Related Pain Management.

Lee M, Moon M, Kim C, Park S, Choi M, Jung S Korean J Radiol. 2020; 21(4):422-430.

PMID: 32193890 PMC: 7082664. DOI: 10.3348/kjr.2019.0576.

Spondylodiscitis with Epidural and Psoas Muscle Abscesses as Complications After Transrectal Ultrasound-guided Prostate Biopsy: Report of a Rare Case.

Li C, Li C, Wu S, Cha T, Tang S Eur J Case Rep Intern Med. 2019; 4(8):000694.

PMID: 30755964 PMC: 6346856. DOI: 10.12890/2017_000694.

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