Idiopathic Pulmonary Hemosiderosis With Allergic Asthma Diagnosis in a Pediatric Patient
Overview
Authors
Affiliations
Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder with unknown pathogenesis that usually presents in the first decade of life. As a result of diffuse alveolar hemorrhage, respiratory symptoms such as cough attacks, hemoptysis, dyspnea, and recurrent and refractory iron-deficiency anemia (IDA) are observed. We present an 8-year-old girl who was followed up with recurrent IDA and allergic asthma and later diagnosed with IPH. IPH was confirmed by the presence of hemosiderin-laden macrophages in bronchoalveolar lavage obtained by bronchoscopy and exclusion of the secondary causes of pulmonary hemosiderosis. Glucocorticoids and iron supplementation were started. Clinical and laboratory improvement was observed with therapy. Our case illustrates that refractory/recurrent IDA with any pulmonary symptoms may be the only presenting feature of IPH.
Lendl L, Barton A Animals (Basel). 2024; 14(23).
PMID: 39682469 PMC: 11640047. DOI: 10.3390/ani14233504.
Anaemia and respiratory failure in a child: can it be idiopathic pulmonary haemosiderosis?.
Ahmed M, Raj D, Kumar A, Kumar A BMJ Case Rep. 2017; 2017.
PMID: 28512100 PMC: 5612269. DOI: 10.1136/bcr-2017-219431.
Idiopathic pulmonary haemosiderosis in paediatric patients: how to make an early diagnosis.
Castellazzi L, Patria M, Frati G, Esposito A, Esposito S Ital J Pediatr. 2016; 42(1):86.
PMID: 27644948 PMC: 5029079. DOI: 10.1186/s13052-016-0296-x.