Tropical and Travel-associated Norovirus: Current Concepts

Overview

Journal Curr Opin Infect Dis

Specialty Infectious Diseases

Date 2015 Aug 4

PMID 26237546

Citations 7

Authors

Sarah-Blythe Ballard

Mayuko Saito

Andrew J Mirelman

Caryn Bern

Robert H Gilman

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: We highlight recent advances relevant to understanding norovirus infections in the tropics, both in populations living in developing settings and travelers to these regions.

Recent Findings: Because of the decrease in diarrheal disease associated with the global rollout of vaccines against rotavirus, norovirus is emerging as the predominant cause of diarrhea morbidity among children in the tropics, and evidence suggests that it contributes to adult disease in endemic populations and travelers. In addition to identifying potential target populations for preventive measures, we provide an update on norovirus vaccine development and concepts related to their implementation in low-income and middle-income countries.

Summary: These current concepts related to norovirus-attributable disease burden, clinical significance, and economic impact can potentially be applied to tailoring efforts to prevent and mitigate the effects of this important enteropathogen.

Citing Articles

Norovirus-Associated Gastroenteritis Vesikari Score and Pre-Existing Salivary IgA in Young Children from Rural South Africa.

Kabue J, Khumela R, Meader E, Moraes M, Traore A, Potgieter N Viruses. 2023; 15(11).

PMID: 38005863 PMC: 10674611. DOI: 10.3390/v15112185.

Tuft cells are key mediators of interkingdom interactions at mucosal barrier surfaces.

Strine M, Wilen C PLoS Pathog. 2022; 18(3):e1010318.

PMID: 35271673 PMC: 8912186. DOI: 10.1371/journal.ppat.1010318.

Enteropathogen Changes After Rotavirus Vaccine Scale-up.

Ballard S, Requena D, Mayta H, Sanchez G, Oyola-Lozada M, Colquechagua Aliaga F Pediatrics. 2021; 149(1).

PMID: 34918158 PMC: 9647525. DOI: 10.1542/peds.2020-049884.

Application of a cost-effectiveness analysis of pathogen-specific vaccines against gastroenteritis to a military population in a developing country setting.

Ballard S, Tallant A, Guerra R, Quigley D, Stiegmann R, Mirelman A Vaccine. 2020; 38(10):2292-2297.

PMID: 32019702 PMC: 9423028. DOI: 10.1016/j.vaccine.2020.01.075.

Estimating the incidence of norovirus acute gastroenteritis among US and European international travelers to areas of moderate to high risk of traveler's diarrhea: a prospective cohort study protocol.

Lindsay L, DuPont H, Moe C, Alberer M, Hatz C, Kirby A BMC Infect Dis. 2018; 18(1):605.

PMID: 30509202 PMC: 6276235. DOI: 10.1186/s12879-018-3461-6.

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