IOP Telemetry in the Nonhuman Primate

Overview

Journal Exp Eye Res

Specialty Ophthalmology

Date 2015 Jul 29

PMID 26216571

Citations 29

Authors

J Crawford Downs

Affiliations

Soon will be listed here.

Abstract

This review is focused on continuous IOP monitoring using telemetry systems in the nonhuman primate (NHP), presented in the context that IOP fluctuations at various timescales may be involved in glaucoma pathogenesis and progression. We use glaucoma as the primary framework to discuss how the dynamic nature of IOP might change with age, racial heritage, and disease in the context of glaucoma susceptibility and progression. We focus on the limited work that has been published in IOP telemetry in NHPs, as well as the emerging data and approaches. We review the ongoing efforts to measure continuous IOP, and the strengths, weaknesses and general pitfalls of the various approaches.

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References

Rochtchina E, Mitchell P, Wang J . Relationship between age and intraocular pressure: the Blue Mountains Eye Study. Clin Exp Ophthalmol. 2002; 30(3):173-5. DOI: 10.1046/j.1442-9071.2002.00519.x. View

Bengtsson B, Leske M, Hyman L, Heijl A . Fluctuation of intraocular pressure and glaucoma progression in the early manifest glaucoma trial. Ophthalmology. 2006; 114(2):205-9. DOI: 10.1016/j.ophtha.2006.07.060. View

Koutsonas A, Walter P, Roessler G, Plange N . Implantation of a novel telemetric intraocular pressure sensor in patients with glaucoma (ARGOS study): 1-year results. Invest Ophthalmol Vis Sci. 2015; 56(2):1063-9. DOI: 10.1167/iovs.14-14925. View

Dastiridou A, Ginis H, De Brouwere D, Tsilimbaris M, Pallikaris I . Ocular rigidity, ocular pulse amplitude, and pulsatile ocular blood flow: the effect of intraocular pressure. Invest Ophthalmol Vis Sci. 2009; 50(12):5718-22. DOI: 10.1167/iovs.09-3760. View

Kaufmann C, Bachmann L, Robert Y, Thiel M . Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry. Arch Ophthalmol. 2006; 124(8):1104-8. DOI: 10.1001/archopht.124.8.1104. View

Quigley H, Broman A . The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006; 90(3):262-7. PMC: 1856963. DOI: 10.1136/bjo.2005.081224. View

Mottet B, Aptel F, Romanet J, Hubanova R, Pepin J, Chiquet C . 24-hour intraocular pressure rhythm in young healthy subjects evaluated with continuous monitoring using a contact lens sensor. JAMA Ophthalmol. 2013; 131(12):1507-16. DOI: 10.1001/jamaophthalmol.2013.5297. View

Medeiros F, Weinreb R, Zangwill L, Alencar L, Sample P, Vasile C . Long-term intraocular pressure fluctuations and risk of conversion from ocular hypertension to glaucoma. Ophthalmology. 2007; 115(6):934-40. PMC: 2848165. DOI: 10.1016/j.ophtha.2007.08.012. View

Girard M, Suh J, Bottlang M, Burgoyne C, Crawford Downs J . Biomechanical changes in the sclera of monkey eyes exposed to chronic IOP elevations. Invest Ophthalmol Vis Sci. 2011; 52(8):5656-69. PMC: 3176060. DOI: 10.1167/iovs.10-6927. View

10.

Melki S, Todani A, Cherfan G . An implantable intraocular pressure transducer: initial safety outcomes. JAMA Ophthalmol. 2014; 132(10):1221-5. DOI: 10.1001/jamaophthalmol.2014.1739. View

11.

McLAREN J, Bachman L, Brubaker R . Comparison of effects of topical ibopamine and epinephrine on the circadian rhythm of intraocular pressure of the rabbit eye as measured by telemetry. J Ocul Pharmacol Ther. 1999; 15(2):107-16. DOI: 10.1089/jop.1999.15.107. View

12.

Miglior S, Pfeiffer N, Torri V, Zeyen T, Cunha-Vaz J, Adamsons I . Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study. Ophthalmology. 2006; 114(1):3-9. DOI: 10.1016/j.ophtha.2006.05.075. View

13.

Punjabi O, Ho H, Kniestedt C, Bostrom A, Stamper R, Lin S . Intraocular pressure and ocular pulse amplitude comparisons in different types of glaucoma using dynamic contour tonometry. Curr Eye Res. 2006; 31(10):851-62. DOI: 10.1080/02713680600899887. View

14.

Crawford Downs J, Suh J, Thomas K, Bellezza A, Hart R, Burgoyne C . Viscoelastic material properties of the peripapillary sclera in normal and early-glaucoma monkey eyes. Invest Ophthalmol Vis Sci. 2005; 46(2):540-6. DOI: 10.1167/iovs.04-0114. View

15.

Gordon M, Beiser J, Brandt J, Heuer D, Higginbotham E, Johnson C . The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002; 120(6):714-20; discussion 829-30. DOI: 10.1001/archopht.120.6.714. View

16.

Rudnicka A, Mt-Isa S, Owen C, Cook D, Ashby D . Variations in primary open-angle glaucoma prevalence by age, gender, and race: a Bayesian meta-analysis. Invest Ophthalmol Vis Sci. 2006; 47(10):4254-61. DOI: 10.1167/iovs.06-0299. View

17.

Bengtsson B, Heijl A . Diurnal IOP fluctuation: not an independent risk factor for glaucomatous visual field loss in high-risk ocular hypertension. Graefes Arch Clin Exp Ophthalmol. 2005; 243(6):513-8. DOI: 10.1007/s00417-004-1103-8. View

18.

Liu J, Kripke D, Hoffman R, Twa M, Loving R, Rex K . Nocturnal elevation of intraocular pressure in young adults. Invest Ophthalmol Vis Sci. 1998; 39(13):2707-12. View

19.

Coleman D, TROKEL S . Direct-recorded intraocular pressure variations in a human subject. Arch Ophthalmol. 1969; 82(5):637-40. DOI: 10.1001/archopht.1969.00990020633011. View

20.

Hoffmann E, Grus F, Pfeiffer N . Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry and contact lens tonometry. BMC Ophthalmol. 2004; 4:4. PMC: 394329. DOI: 10.1186/1471-2415-4-4. View