Synthesis, Spectroscopic Investigations (X-ray, NMR and TD-DFT), Antimicrobial Activity and Molecular Docking of 2,6-bis(hydroxy(phenyl)methyl)cyclohexanone

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2015 Jul 22

PMID 26197312

Citations 1

Authors

Assem Barakat

Hazem A Ghabbour

Abdullah Mohammed Al-Majid

Saied M Soliman

M Ali

Yahia Nasser Mabkhot

Mohammed Rafi Shaik

Hoong-Kun Fun

Affiliations

Soon will be listed here.

Abstract

The synthesis of 2,6-bis(hydroxy(phenyl)methyl)cyclohexanone 1 is described. The molecular structure of the title compound 1 was confirmed by NMR, FT-IR, MS, CHN microanalysis, and X-ray crystallography. The molecular structure was also investigated by a set of computational studies and found to be in good agreement with the experimental data obtained from the various spectrophotometric techniques. The antimicrobial activity and molecular docking of the synthesized compound was investigated.

Citing Articles

Computational studies of 2-(4-oxo-3-phenylthiazolidin-2-ylidene)malononitrile.

Mabkhot Y, Al-Showiman S, Barakat A, Soliman S, Kheder N, Alharbi M BMC Chem. 2019; 13(1):25.

PMID: 31384774 PMC: 6661733. DOI: 10.1186/s13065-019-0542-6.

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