Comparison of Breast Simultaneous Integrated Boost (SIB) Radiotherapy Techniques

Overview

Journal Radiat Oncol

Publisher Biomed Central

Specialties Oncology
Radiology

Date 2015 Jul 10

PMID 26156086

Citations 25

Authors

Moamen M O M Aly

Gerhard Glatting

Lennart Jahnke

Frederik Wenz

Yasser Abo-Madyan

Affiliations

Soon will be listed here.

Abstract

Purpose: To dosimetrically evaluate different breast SIB techniques with respect to target coverage and organs at risk (OARs) doses.

Methods: Four IMRT techniques were compared in 12 patients. Three techniques employ tangential whole breast irradiation with either two coplanar fields (T-2F), or four non-coplanar fields (T-NC), or one Volumetric Modulated Arc Therapy (T-VMAT) for the boost volume. The fourth technique is a fully-modulated VMAT technique (f-VMAT). Dosimetric parameters were compared for the boost and breast target volumes as well as OARs. Delivery efficiency was analysed based on number of monitor units (MUs) and estimated delivery time.

Results: T-VMAT and f-VMAT ranked highest with respect to integral assessment of boost and breast treatment quality measures. T-VMAT significantly outperformed f-VMAT with respect to ipsi-lateral lung and left-sided patients' heart volumes ≥ 5 Gy (35 % ± 5 % vs. 52 % ± 6 % and 11 % ± 5 % vs. 22 % ± 6 %, respectively). f-VMAT significantly outperformed T-VMAT with respect to ipsi-lateral lung volume ≥ 20 Gy (13 % ± 2 % vs. 15 % ± 3 %) and heart volume ≥ 30 Gy in left breast cancer (0 % ± 0 % vs. 1 % ± 1 %). T-VMAT and f-VMAT needed 442 ± 58 and 1016 ± 152 MUs, respectively.

Conclusions: The hybrid T-VMAT is considered the technique of choice due to its balance of quality, efficiency and dose to OARs.

Citing Articles

Technical feasibility of delivering a simultaneous integrated boost in partial breast irradiation.

Burton A, Cassar T, Glenn C, Byrne K Phys Imaging Radiat Oncol. 2024; 32:100659.

PMID: 39526021 PMC: 11550061. DOI: 10.1016/j.phro.2024.100659.

Ultra-Hypofractionated Whole Breast Radiotherapy with Automated Hybrid-VMAT Technique: A Pilot Study on Safety, Skin Toxicity and Aesthetic Outcomes.

Boccardi M, Cilla S, Fanelli M, Romano C, Bonome P, Ferro M Breast Cancer (Dove Med Press). 2024; 16:611-619.

PMID: 39310783 PMC: 11415599. DOI: 10.2147/BCTT.S470417.

The use of Hybrid Techniques in Whole-Breast Radiotherapy: A Systematic Review.

Karaca S Technol Cancer Res Treat. 2022; 21:15330338221143937.

PMID: 36537067 PMC: 9772967. DOI: 10.1177/15330338221143937.

The clinical outcome of postoperative radiotherapy using hybrid planning technique in left breast cancer after breast-conserving surgery.

Wei T, Yeh H, Lin J, Hung C Cancer Med. 2022; 12(5):5364-5371.

PMID: 36250354 PMC: 10028103. DOI: 10.1002/cam4.5358.

Comparison of Breast Cancer Radiotherapy Techniques Regarding Secondary Cancer Risk and Normal Tissue Complication Probability - Modelling and Measurements Using a 3D-Printed Phantom.

Vogel M, Gade J, Timm B, Schurmann M, Auerbach H, Nusken F Front Oncol. 2022; 12:892923.

PMID: 35965556 PMC: 9365503. DOI: 10.3389/fonc.2022.892923.

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