Recent Advances in Brucella Abortus Vaccines

Overview

Journal Vet Res

Publisher Biomed Central

Specialty Veterinary Medicine

Date 2015 Jul 10

PMID 26155935

Citations 62

Authors

Elaine M S Dorneles

Nammalwar Sriranganathan

Andrey P Lage

Affiliations

Soon will be listed here.

Abstract

Brucella abortus vaccines play a central role in bovine brucellosis control/eradication programs and have been successfully used worldwide for decades. Strain 19 and RB51 are the approved B. abortus vaccines strains most commonly used to protect cattle against infection and abortion. However, due to some drawbacks shown by these vaccines much effort has been undertaken for the development of new vaccines, safer and more effective, that could also be used in other susceptible species of animals. In this paper, we present a review of the main aspects of the vaccines that have been used in the brucellosis control over the years and the current research advances in the development of new B. abortus vaccines.

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