Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2015 Jul 9

PMID 26153774

Citations 54

Authors

Ti-Hsuan Ku

Tiantian Zhang

Hua Luo

Tony M Yen

Ping-Wei Chen

Yuanyuan Han

Yu-Hwa Lo

Affiliations

Soon will be listed here.

Abstract

Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities related to nucleic acid-based aptamer techniques that have been reported in the past two decades. Limitations of aptamers and possible approaches to overcome these limitations are also discussed.

Citing Articles

Aptamers: precision tools for diagnosing and treating infectious diseases.

Sujith S, Naresh R, Srivisanth B, Sajeevan A, Rajaramon S, David H Front Cell Infect Microbiol. 2024; 14:1402932.

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Comparative Analysis of QCM and Electrochemical Aptasensors for SARS-CoV-2 Detection.

Nemcekova K, Korcekova J, Svitkova V, Baraniak D, Domsicova M, Melnikova E Biosensors (Basel). 2024; 14(9).

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Crossing the Halfway Point: Aptamer-Based, Highly Multiplexed Assay for the Assessment of the Proteome.

Kraemer S, Schneider D, Paterson C, Perry D, Westacott M, Hagar Y J Proteome Res. 2024; 23(11):4771-4788.

PMID: 39038188 PMC: 11536431. DOI: 10.1021/acs.jproteome.4c00411.

New Insights into Aptamers: An Alternative to Antibodies in the Detection of Molecular Biomarkers.

Domsicova M, Korcekova J, Poturnayova A, Breier A Int J Mol Sci. 2024; 25(13).

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