Prevalence of Malaria Parasites in Adults and Its Determinants in Malaria Endemic Area of Kisumu County, Kenya

Overview

Journal Malar J

Publisher Biomed Central

Specialty Tropical Medicine

Date 2015 Jul 9

PMID 26152272

Citations 49

Authors

Rachel Jenkins

Raymond Omollo

Michael Ongecha

Peter Sifuna

Caleb Othieno

Linnet Ongeri

James Kingora

Bernhards Ogutu

Affiliations

Soon will be listed here.

Abstract

Background: The prevalence of malaria parasites in adults in Africa is less well researched than in children. Therefore, a demographic surveillance site was used to conduct a household survey of adults in the malaria endemic area of Maseno division in Kisumu County near Lake Victoria.

Methods: A random survey of 1,190 adults living in a demographic health surveillance site in a malaria endemic area of 70,805 population size was conducted, measuring presence of malaria parasites by slide microscopy. Data were analysed using STATA to calculate the prevalence of malaria and associated risk factors.

Results: The adult prevalence of presence of malaria parasites in Maseno was 28% (95% CI: 25.4-31.0%). Gender was a significant sociodemographic risk factor in both univariate (OR 1.5, p = 0.005) and multivariate (OR 1.4, p = 0.019) analyses. Females were 50% more likely to have malaria than men.

Conclusions: Presence of malaria parasites is common in the adult population of this endemic area, and the rate is greatly increased in women. The presence of such an adult pool of malaria parasites represents a key reservoir factor in transmission of parasites to children, and is relevant for plans to eradicate malaria.

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References

Trape J, Tall A, Sokhna C, Ly A, Diagne N, Ndiath O . The rise and fall of malaria in a West African rural community, Dielmo, Senegal, from 1990 to 2012: a 22 year longitudinal study. Lancet Infect Dis. 2014; 14(6):476-88. DOI: 10.1016/S1473-3099(14)70712-1. View

Sifuna P, Oyugi M, Ogutu B, Andagalu B, Otieno A, Owira V . Health & demographic surveillance system profile: The Kombewa health and demographic surveillance system (Kombewa HDSS). Int J Epidemiol. 2014; 43(4):1097-104. PMC: 4258789. DOI: 10.1093/ije/dyu139. View

Snow R . Global malaria eradication and the importance of Plasmodium falciparum epidemiology in Africa. BMC Med. 2015; 13:23. PMC: 4314741. DOI: 10.1186/s12916-014-0254-7. View

Noor A, Gething P, Alegana V, Patil A, Hay S, Muchiri E . The risks of malaria infection in Kenya in 2009. BMC Infect Dis. 2009; 9:180. PMC: 2783030. DOI: 10.1186/1471-2334-9-180. View

Keen J, Serghides L, Ayi K, Patel S, Ayisi J, van Eijk A . HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites. PLoS Med. 2007; 4(5):e181. PMC: 1880852. DOI: 10.1371/journal.pmed.0040181. View

Ned R, Price A, Crawford S, Ayisi J, van Eijk A, Otieno J . Effect of placental malaria and HIV infection on the antibody responses to Plasmodium falciparum in infants. J Infect Dis. 2008; 198(11):1609-19. DOI: 10.1086/593066. View

Tay S, Badu K, Mensah A, Gbedema S . The prevalence of malaria among HIV seropositive individuals and the impact of the co- infection on their hemoglobin levels. Ann Clin Microbiol Antimicrob. 2015; 14:10. PMC: 4355357. DOI: 10.1186/s12941-015-0064-6. View

Alonso P, Brown G, Arevalo-Herrera M, Binka F, Chitnis C, Collins F . A research agenda to underpin malaria eradication. PLoS Med. 2011; 8(1):e1000406. PMC: 3026687. DOI: 10.1371/journal.pmed.1000406. View

Murray C, Rosenfeld L, Lim S, Andrews K, Foreman K, Haring D . Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet. 2012; 379(9814):413-31. DOI: 10.1016/S0140-6736(12)60034-8. View

10.

Jenkins R, Njenga F, Okonji M, Kigamwa P, Baraza M, Ayuyo J . Psychotic symptoms in Kenya--prevalence, risk factors, and relationship with common mental disorders. Int J Environ Res Public Health. 2012; 9(5):1748-56. PMC: 3386585. DOI: 10.3390/ijerph9051748. View

11.

Mayor A, Aponte J, Fogg C, Saute F, Greenwood B, Dgedge M . The epidemiology of malaria in adults in a rural area of southern Mozambique. Malar J. 2007; 6:3. PMC: 1796885. DOI: 10.1186/1475-2875-6-3. View

12.

Morris S, Carletto C, Hoddinott J, Christiaensen L . Validity of rapid estimates of household wealth and income for health surveys in rural Africa. J Epidemiol Community Health. 2000; 54(5):381-7. PMC: 1731675. DOI: 10.1136/jech.54.5.381. View

13.

Bousema J, Gouagna L, Drakeley C, Meutstege A, Okech B, Akim I . Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya. Malar J. 2004; 3:18. PMC: 441400. DOI: 10.1186/1475-2875-3-18. View

14.

Baird J, Jones T, Danudirgo E, Annis B, Bangs M, Basri H . Age-dependent acquired protection against Plasmodium falciparum in people having two years exposure to hyperendemic malaria. Am J Trop Med Hyg. 1991; 45(1):65-76. DOI: 10.4269/ajtmh.1991.45.65. View

15.

Snow R, Craig M, Deichmann U, Marsh K . Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population. Bull World Health Organ. 1999; 77(8):624-40. PMC: 2557714. View

16.

Alves F, Gil L, Marrelli M, Ribolla P, Camargo E, Silva L . Asymptomatic carriers of Plasmodium spp. as infection source for malaria vector mosquitoes in the Brazilian Amazon. J Med Entomol. 2005; 42(5):777-9. DOI: 10.1093/jmedent/42.5.777. View

17.

Adjuik M, Smith T, Clark S, Todd J, Garrib A, Kinfu Y . Cause-specific mortality rates in sub-Saharan Africa and Bangladesh. Bull World Health Organ. 2006; 84(3):181-8. PMC: 2627285. DOI: 10.2471/blt.05.026492. View

18.

Jenkins R, Njenga F, Okonji M, Kigamwa P, Baraza M, Ayuyo J . Prevalence of common mental disorders in a rural district of Kenya, and socio-demographic risk factors. Int J Environ Res Public Health. 2012; 9(5):1810-9. PMC: 3386589. DOI: 10.3390/ijerph9051810. View