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Unfolded Protein Response in Plants: One Master, Many Questions

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Specialty Biology
Date 2015 Jul 8
PMID 26149756
Citations 36
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Abstract

To overcome endoplasmic reticulum (ER) stress, ER-localized stress sensors actuate distinct downstream organelle-nucleus signaling pathways to invoke a cytoprotective response, known as the unfolded protein response (UPR). Compared to yeast and metazoans, plant UPR studies are more recent but nevertheless fascinating. Here we discuss recent discoveries in plant UPR, highlight conserved and unique features of the plant UPR as well as critical yet-open questions whose answers will likely make significant contributions to the understanding plant ER stress management.

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References
1.
Leborgne-Castel N, Crofts A, Denecke J . Overexpression of BiP in tobacco alleviates endoplasmic reticulum stress. Plant Cell. 1999; 11(3):459-70. PMC: 144191. DOI: 10.1105/tpc.11.3.459. View

2.
Mori K, Ogawa N, Kawahara T, Yanagi H, Yura T . mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response. Proc Natl Acad Sci U S A. 2000; 97(9):4660-5. PMC: 18289. DOI: 10.1073/pnas.050010197. View

3.
Harding H, Zhang Y, Bertolotti A, Zeng H, Ron D . Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell. 2000; 5(5):897-904. DOI: 10.1016/s1097-2765(00)80330-5. View

4.
Koizumi N, Martinez I, Kimata Y, Kohno K, Sano H, Chrispeels M . Molecular characterization of two Arabidopsis Ire1 homologs, endoplasmic reticulum-located transmembrane protein kinases. Plant Physiol. 2001; 127(3):949-62. PMC: 129266. View

5.
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K . XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 2002; 107(7):881-91. DOI: 10.1016/s0092-8674(01)00611-0. View