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Dissecting the Role of Smooth Muscle Cells Versus Pericytes in Regulating Cerebral Blood Flow Using In Vivo Optical Imaging

Overview
Journal Neuron
Publisher Cell Press
Specialty Neurology
Date 2015 Jul 4
PMID 26139364
Citations 6
Authors
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Abstract

The brain regulates blood flow to match energy demand to nutrient supply. In this issue of Neuron, using in vivo optical imaging and optogenetics, Hill et al. (2015) report that arteriolar smooth muscle cells are key players in regulating cerebral blood flow in the healthy state and contribute to the "no reflow" phenomenon after ischemic stroke.

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