Echinococcus Multilocularis in Kyrgyzstan: Similarity in the Asian EmsB Genotypic Profiles from Village Populations of Eastern Mole Voles (Ellobius Tancrei) and Dogs in the Alay Valley

Overview

Journal J Helminthol

Specialty Parasitology

Date 2015 Jul 4

PMID 26137938

Citations 12

Authors

E Afonso

J Knapp

N Tete

G Umhang

D Rieffel

F van Kesteren

I Ziadinov

P S Craig

P R Torgerson

P Giraudoux

Affiliations

Soon will be listed here.

Abstract

Echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonosis of public health concern in central Asia and western China. In the present study, one of 42 Eastern mole voles (Ellobius tancrei) caught in Sary Mogol (Alay valley, southern Kyrgyzstan) presented liver lesions with E. multilocularis from which the EmsB target was amplified. The Asian profile obtained was almost identical to one amplified from domestic dog faeces collected in a nearby village. This observation adds additional information to the potential role of E. tancrei in the transmission of E. multilocularis, and to the known distribution range of E. multilocularis (Asian strain) in central Asia.

Citing Articles

Echinococcus granulosus sensu lato control measures: a specific focus on vaccines for both definitive and intermediate hosts.

Borhani M, Fathi S, Harandi M, Casulli A, Ding J, Liu M Parasit Vectors. 2024; 17(1):533.

PMID: 39716337 PMC: 11665232. DOI: 10.1186/s13071-024-06581-2.

species in wildlife.

Romig T, Wassermann M Int J Parasitol Parasites Wildl. 2024; 23:100913.

PMID: 38405672 PMC: 10884515. DOI: 10.1016/j.ijppaw.2024.100913.

Helminth and protozoan parasites of subterranean rodents (Chordata, Mammalia, Rodentia) of the world.

Dursahinhan A, Kenkel D, Gardner S Zookeys. 2023; 1151:159-203.

PMID: 37235179 PMC: 10207929. DOI: 10.3897/zookeys.1151.97126.

A new species of from (Rodentia: Cricetidae) in Mongolia.

Dursahinhan A, Brooks D, Botero-Canola S, Gardner S Parasitology. 2022; :1-26.

PMID: 35287771 PMC: 10090593. DOI: 10.1017/S0031182022000294.

Assessment of the Genetic Diversity of from Copro-Isolated Eggs.

Knapp J, Malik Da Silva A, Courquet S, Millon L Pathogens. 2021; 10(10).

PMID: 34684245 PMC: 8541330. DOI: 10.3390/pathogens10101296.

References

Giraudoux P, Raoul F, Afonso E, Ziadinov I, Yang Y, Li L . Transmission ecosystems of Echinococcus multilocularis in China and Central Asia. Parasitology. 2013; 140(13):1655-66. PMC: 3806041. DOI: 10.1017/S0031182013000644. View

Knapp J, Bart J, Glowatzki M, Ito A, Gerard S, Maillard S . Assessment of use of microsatellite polymorphism analysis for improving spatial distribution tracking of echinococcus multilocularis. J Clin Microbiol. 2007; 45(9):2943-50. PMC: 2045259. DOI: 10.1128/JCM.02107-06. View

Ziadinov I, Mathis A, Trachsel D, Rysmukhambetova A, Abdyjaparov T, Kuttubaev O . Canine echinococcosis in Kyrgyzstan: using prevalence data adjusted for measurement error to develop transmission dynamics models. Int J Parasitol. 2008; 38(10):1179-90. PMC: 2527539. DOI: 10.1016/j.ijpara.2008.01.009. View

Knapp J, Bart J, Giraudoux P, Glowatzki M, Breyer I, Raoul F . Genetic diversity of the cestode Echinococcus multilocularis in red foxes at a continental scale in Europe. PLoS Negl Trop Dis. 2009; 3(6):e452. PMC: 2685985. DOI: 10.1371/journal.pntd.0000452. View

Eckert J, Deplazes P . Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev. 2004; 17(1):107-35. PMC: 321468. DOI: 10.1128/CMR.17.1.107-135.2004. View

Vuitton D, Zhou H, Bresson-Hadni S, Wang Q, Piarroux M, Raoul F . Epidemiology of alveolar echinococcosis with particular reference to China and Europe. Parasitology. 2004; 127 Suppl:S87-107. View

Bowles J, McManus D . NADH dehydrogenase 1 gene sequences compared for species and strains of the genus Echinococcus. Int J Parasitol. 1993; 23(7):969-72. DOI: 10.1016/0020-7519(93)90065-7. View

Bretagne S, Assouline B, Vidaud D, Houin R, Vidaud M . Echinococcus multilocularis: microsatellite polymorphism in U1 snRNA genes. Exp Parasitol. 1996; 82(3):324-8. DOI: 10.1006/expr.1996.0040. View

Haag K, Zaha A, Araujo A, Gottstein B . Reduced genetic variability within coding and non-coding regions of the Echinococcus multilocularis genome. Parasitology. 1997; 115 ( Pt 5):521-9. DOI: 10.1017/s0031182097001649. View

10.

Giraudoux P, Pleydell D, Raoul F, Quere J, Wang Q, Yang Y . Transmission ecology of Echinococcus multilocularis: what are the ranges of parasite stability among various host communities in China?. Parasitol Int. 2005; 55 Suppl:S237-46. DOI: 10.1016/j.parint.2005.11.036. View

11.

Torgerson P, Oguljahan B, Muminov A, Karaeva R, Kuttubaev O, Aminjanov M . Present situation of cystic echinococcosis in Central Asia. Parasitol Int. 2005; 55 Suppl:S207-12. DOI: 10.1016/j.parint.2005.11.032. View

12.

Bart J, Knapp J, Gottstein B, El-Garch F, Giraudoux P, Glowatzki M . EmsB, a tandem repeated multi-loci microsatellite, new tool to investigate the genetic diversity of Echinococcus multilocularis. Infect Genet Evol. 2006; 6(5):390-400. DOI: 10.1016/j.meegid.2006.01.006. View

13.

van Kesteren F, Mastin A, Mytynova B, Ziadinov I, Boufana B, Torgerson P . Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan. Parasitology. 2013; 140(13):1674-84. PMC: 3806042. DOI: 10.1017/S0031182013001182. View

14.

Umhang G, Knapp J, Hormaz V, Raoul F, Boue F . Using the genetics of Echinococcus multilocularis to trace the history of expansion from an endemic area. Infect Genet Evol. 2014; 22:142-9. DOI: 10.1016/j.meegid.2014.01.018. View

15.

Liccioli S, Giraudoux P, Deplazes P, Massolo A . Wilderness in the 'city' revisited: different urbes shape transmission of Echinococcus multilocularis by altering predator and prey communities. Trends Parasitol. 2015; 31(7):297-305. DOI: 10.1016/j.pt.2015.04.007. View

16.

Ziadinov I, Deplazes P, Mathis A, Mutunova B, Abdykerimov K, Nurgaziev R . Frequency distribution of Echinococcus multilocularis and other helminths of foxes in Kyrgyzstan. Vet Parasitol. 2010; 171(3-4):286-92. PMC: 2903646. DOI: 10.1016/j.vetpar.2010.04.006. View

17.

Knapp J, Guislain M, Bart J, Raoul F, Gottstein B, Giraudoux P . Genetic diversity of Echinococcus multilocularis on a local scale. Infect Genet Evol. 2008; 8(3):367-73. DOI: 10.1016/j.meegid.2008.02.010. View

18.

Usubalieva J, Minbaeva G, Ziadinov I, Deplazes P, Torgerson P . Human alveolar echinococcosis in Kyrgyzstan. Emerg Infect Dis. 2013; 19(7):1095-7. PMC: 3713972. DOI: 10.3201/eid1907.121405. View