Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2015 Jul 1

PMID 26125021

Citations 68

Authors

Yueh-Hsia Luo

Louis W Chang

Pinpin Lin

Affiliations

Soon will be listed here.

Abstract

Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models.

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