[One Case of Multiple Myeloma with Central Never System Infiltration]

Objective: To analyses and summarize a case of multiple myeloma with disseminated infiltration in central nervous system.

Methods: The results of laboratorial examination and clinical data were analyzed and compared in the light of published literatures.

Results: The headache and diplopia were caused by infiltration of multiple myeloma cells to the central nervous system. Unlike those reported in the literatures, this case was a rare case of disseminated infiltration inside the brain, and plasma cells were CD56+, this patient has not yet accepted any multiple myeloma-associated treatment as like that reported in the literatures. And different from cases reported, this patient showed a good response to the intrathecal chemotherapy.

Conclusion: Whether this good response is due to a heterogeneity of MM or effect of treatment-associated drug is still to be decided.