Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3: Protocol for a Longitudinal Study

Overview

Journal BMJ Open

Specialty General Medicine

Date 2015 Jun 25

PMID 26105029

Citations 7

Authors

O A Alabas

R M West

R G Gillott

R Khatib

A S Hall

C P Gale

Affiliations

Soon will be listed here.

Abstract

Introduction: Patients with cardiovascular disease are living longer and are more frequently accessing healthcare resources. The Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3 national study is designed to improve understanding of the effect of quality of care on health-related outcomes for patients hospitalised with acute coronary syndrome (ACS).

Methods And Analysis: EMMACE-3 is a longitudinal study of 5556 patients hospitalised with an ACS in England. The study collects repeated measures of health-related quality of life, information about medications and patient adherence profiles, a survey of hospital facilities, and morbidity and mortality data from linkages to multiple electronic health records. Together with EMMACE-3X and EMMACE-4, EMMACE-3 will assimilate detailed information for about 13 000 patients across more than 60 hospitals in England.

Ethics And Dissemination: EMMACE-3 was given a favourable ethical opinion by Leeds (West) Research Ethics committee (REC reference: 10/H131374). On successful application, study data will be shared with academic collaborators. The findings from EMMACE-3 will be disseminated through peer-reviewed publications, at scientific conferences, the media, and through patient and public involvement.

Study Registration Number: ClinicalTrials.gov Identifier: NCT01808027. Information about the study is also available at EMMACE.org.

Citing Articles

Associations of health-related quality of life with major adverse cardiovascular and cerebrovascular events for individuals with ischaemic heart disease: systematic review, meta-analysis and evidence mapping.

Soloveva A, Gale C, Han N, Hurdus B, Aktaa S, Palin V Open Heart. 2023; 10(2).

PMID: 37890894 PMC: 10619110. DOI: 10.1136/openhrt-2023-002452.

Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) Longitudinal Cohort.

Munyombwe T, Dondo T, Hall M, Nadarajah R, Hurdus B, Aktaa S Eur Heart J Qual Care Clin Outcomes. 2023; 9(5):442-446.

PMID: 37451698 PMC: 10405135. DOI: 10.1093/ehjqcco/qcad040.

Sex differences in health-related quality of life trajectories following myocardial infarction: national longitudinal cohort study.

Dondo T, Munyombwe T, Hall M, Hurdus B, Soloveva A, Oliver G BMJ Open. 2022; 12(11):e062508.

PMID: 36351712 PMC: 9644325. DOI: 10.1136/bmjopen-2022-062508.

Anemia or other comorbidities? using machine learning to reveal deeper insights into the drivers of acute coronary syndromes in hospital admitted patients.

Alsayegh F, Alkhamis M, Ali F, Attur S, Fountain-Jones N, Zubaid M PLoS One. 2022; 17(1):e0262997.

PMID: 35073375 PMC: 8786175. DOI: 10.1371/journal.pone.0262997.

Statins for primary prevention among elderly men and women.

Bergami M, Cenko E, Yoon J, Mendieta G, Kedev S, Zdravkovic M Cardiovasc Res. 2021; 118(14):3000-3009.

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