» Articles » PMID: 26060718

Factors Associated with Hepatitis C Infection Among Chronic HCV Egyptian Patients

Overview
Date 2015 Jun 11
PMID 26060718
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Identification of risk factors of acute hepatitis C virus (HCV) infection in Egypt is crucial for developing appropriate prevention strategies. There are few community-based studies on the epidemiology and risk factors of hepatitis C infection in Egypt, which could not provide enough information. Clear identification of past and current risk factors for infection is of utmost importance so that intervention programs can be appropriately focused. This study aims to provide up-to-date information about changes in the incidence of individual risk factors for HCV infection transmission in Egypt.

Methods: A total of 396 chronic HCV patients on follow-up treatment at liver center in El-Qabbary General Hospital in Alexandria were evaluated retrospectively regarding the potential iatrogenic, community acquired and behavioral HCV risk factors. Risk factors for HCV transmission were found in all study populations.

Results: At least three identifiable risk factors were reported by each participant. Some behavioral and community-acquired exposures that entail several risky behaviors particularly, unsafe sexual practices were exclusively established among males. We report a significant decline in prevalence of HCV transmission through blood transfusion, parenteral treatment, hospitalization, surgery, non medicalized circumcision, Hijiama done by informal practitioner, tattooing, folk body piercing and threading, sharing hygiene and sharp items, and the use of communal barber or manicure sets among younger age cluster.

Conclusion: The pattern of risk differed among older patients compared to younger age group suggesting improved medical care and infection control measures and raised public health awareness regarding the different modes of viral transmission.

Citing Articles

Disseminated Staphylococcus aureus infection after scarification wet cupping therapy: a case report and literature review.

Wang Y, Fan H, Huang X, Jiao Y BMC Complement Med Ther. 2023; 23(1):94.

PMID: 36997976 PMC: 10061885. DOI: 10.1186/s12906-023-03932-x.


Unsafe Practices Associated with HCV Infection Among Adults: A Case Control Study.

Heiza M, Elmola K, Salama B Int J Prev Med. 2021; 12:60.

PMID: 34447502 PMC: 8356959. DOI: 10.4103/ijpvm.IJPVM_94_20.


Real-life results of sofosbuvir based therapy in chronic hepatitis C -naïve and -experienced patients in Egypt.

Nagaty A, Abd El-Wahab E PLoS One. 2017; 12(10):e0184654.

PMID: 28981513 PMC: 5628811. DOI: 10.1371/journal.pone.0184654.


Molecular characterization and epidemic history of hepatitis C virus using core sequences of isolates from Central Province, Saudi Arabia.

Shier M, Iles J, El-Wetidy M, Ali H, Al Qattan M PLoS One. 2017; 12(9):e0184163.

PMID: 28863156 PMC: 5580995. DOI: 10.1371/journal.pone.0184163.


Risky exposures and national estimate of HCV seroprevalence among school children in urban Egypt.

Abd El-Wahab E, Abdel Maksoud A, Shatat H, Kotkat A Virusdisease. 2016; 27(4):351-356.

PMID: 28004014 PMC: 5142596. DOI: 10.1007/s13337-016-0345-5.


References
1.
Guerra J, Garenne M, Mohamed M, Fontanet A . HCV burden of infection in Egypt: results from a nationwide survey. J Viral Hepat. 2012; 19(8):560-7. DOI: 10.1111/j.1365-2893.2011.01576.x. View

2.
Medhat A, Shehata M, Magder L, Mikhail N, Nafeh M, Abdel-Hamid M . Hepatitis c in a community in Upper Egypt: risk factors for infection. Am J Trop Med Hyg. 2002; 66(5):633-8. DOI: 10.4269/ajtmh.2002.66.633. View

3.
Ataei B, Hashemipour M, Kassaian N, Hassannejad R, Nokhodian Z, Adibi P . Prevalence of anti HCV infection in patients with Beta-thalassemia in isfahan-iran. Int J Prev Med. 2012; 3(Suppl 1):S118-23. PMC: 3399295. View

4.
Kandeel A, Talaat M, Afifi S, El-Sayed N, Abdel Fadeel M, Hajjeh R . Case control study to identify risk factors for acute hepatitis C virus infection in Egypt. BMC Infect Dis. 2012; 12:294. PMC: 3515403. DOI: 10.1186/1471-2334-12-294. View

5.
Bradshaw D, Matthews G, Danta M . Sexually transmitted hepatitis C infection: the new epidemic in MSM?. Curr Opin Infect Dis. 2012; 26(1):66-72. DOI: 10.1097/QCO.0b013e32835c2120. View