Gut Bacteria and Cancer

Overview

Journal Biochim Biophys Acta

Specialties Biochemistry
Biophysics

Date 2015 Jun 9

PMID 26050963

Citations 31

Authors

Susan E Erdman

Theofilos Poutahidis

Affiliations

Soon will be listed here.

Abstract

Microbiota on the mucosal surfaces of the gastrointestinal (GI) tract greatly outnumbers the cells in the human body. Effects of antibiotics indicate that GI tract bacteria may be determining the fate of distal cancers. Recent data implicate dysregulated host responses to enteric bacteria leading to cancers in extra-intestinal sites. Together these findings point to novel anti-cancer strategies aimed at promoting GI tract homeostasis.

Citing Articles

Suppression of chemically induced mammary cancer by early-life oral administration of cholera toxin in mice is associated with aberrant regulation of Bmp and Notch signaling pathways.

Argyris D, Markaki M, Afaloniati H, Karagiannis G, Poutahidis T, Angelopoulou K Mol Biol Rep. 2025; 52(1):150.

PMID: 39841292 DOI: 10.1007/s11033-025-10271-2.

Gut Microbiota's role in lipoma development: evidence from mendelian randomization.

Li Y, Chen J, Yao H, Xu X, Zheng X, Wang Y Front Genet. 2024; 15:1430671.

PMID: 39619672 PMC: 11604723. DOI: 10.3389/fgene.2024.1430671.

The role of intestinal flora on tumor immunotherapy: recent progress and treatment implications.

Zhou Y, Liu X, Gao W, Luo X, Lv J, Wang Y Heliyon. 2024; 10(1):e23919.

PMID: 38223735 PMC: 10784319. DOI: 10.1016/j.heliyon.2023.e23919.

Mendelian randomization analysis revealed a gut microbiota-mammary axis in breast cancer.

Zhang S, Zhang W, Ren H, Xue R, Wang Z, Wang Z Front Microbiol. 2023; 14:1193725.

PMID: 37680534 PMC: 10482102. DOI: 10.3389/fmicb.2023.1193725.

Influence of the Oral Health Assessment Tool Score on Survival of Patients With Esophageal Cancer.

Tamagawa H, Tamagawa A, Aoyama T, Hashimoto I, Maezawa Y, Hara K In Vivo. 2023; 37(5):2253-2259.

PMID: 37652503 PMC: 10500491. DOI: 10.21873/invivo.13327.

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