An Alternative Method for Generating Arynes from Ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2015 Jun 4

PMID 26039336

Citations 3

Authors

Suguru Yoshida

Yuki Hazama

Yuto Sumida

Takahisa Yano

Takamitsu Hosoya

Affiliations

Soon will be listed here.

Abstract

An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied to a variety of reactions between several arynes and arynophiles. We also demonstrated that the efficiency of aryne generation is significantly affected by the alkali metal countercation of the carbonate.

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