» Articles » PMID: 26034681

HAV in Fresh Vegetables: a Hidden Health Risk in District Mardan, Pakistan

Overview
Journal Springerplus
Date 2015 Jun 3
PMID 26034681
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Hepatitis A is an acute inflammation of the liver caused by the hepatitis A virus (HAV) in human. The path of entry of HAV to the bloodstream is the epithelium of the intestine. Liver inflammation occurs when HAV multiplies within the hepatocytes and Kupffer cells of the liver. HAV is mostly transmitted by contaminated water, fruits and vegetables. The purpose of the current study was to evaluate fresh vegetables raised on the fecal contaminated water for the detection of HAV by PCR method. Twenty nine samples were collected from 13 different locations of district Mardan and screened for the presence of HAV. Village Bajowro near Takht Bhai was the most contaminated site having HAV in all vegetables grown over there. Water samples collected from this area proved to be contaminated with HAV. It may be concluded that fecal contaminated water is unsafe for irrigation because of the health risk associated with such practices.

Citing Articles

Characterisation of the environmental presence of hepatitis A virus in low-income and middle-income countries: a systematic review and meta-analysis.

Kuodi P, Patterson J, Silal S, Hussey G, Kagina B BMJ Open. 2020; 10(9):e036407.

PMID: 32988941 PMC: 7523219. DOI: 10.1136/bmjopen-2019-036407.


Quantitative PCR-based identification of enteric viruses contaminating fresh produce and surface water used for irrigation in Egypt.

Shaheen M, Elmahdy E, Chawla-Sarkar M Environ Sci Pollut Res Int. 2019; 26(21):21619-21628.

PMID: 31129895 DOI: 10.1007/s11356-019-05435-0.


Viral Hepatitis in Pakistan: Past, Present, and Future.

Butt A, Sharif F Euroasian J Hepatogastroenterol. 2017; 6(1):70-81.

PMID: 29201731 PMC: 5578565. DOI: 10.5005/jp-journals-10018-1172.


Virological Quality of Irrigation Water in Leafy Green Vegetables and Berry Fruits Production Chains.

Kokkinos P, Kozyra I, Lazic S, Soderberg K, Vasickova P, Bouwknegt M Food Environ Virol. 2016; 9(1):72-78.

PMID: 27709435 DOI: 10.1007/s12560-016-9264-2.

References
1.
Iritani N, Kaida A, Abe N, Kubo H, Sekiguchi J, Yamamoto S . Detection and genetic characterization of human enteric viruses in oyster-associated gastroenteritis outbreaks between 2001 and 2012 in Osaka City, Japan. J Med Virol. 2014; 86(12):2019-25. DOI: 10.1002/jmv.23883. View

2.
Miura T, Parnaudeau S, Grodzki M, Okabe S, Atmar R, Le Guyader F . Environmental detection of genogroup I, II, and IV noroviruses by using a generic real-time reverse transcription-PCR assay. Appl Environ Microbiol. 2013; 79(21):6585-92. PMC: 3811514. DOI: 10.1128/AEM.02112-13. View

3.
Jean J, Blais B, Darveau A, Fliss I . Detection of hepatitis A virus by the nucleic acid sequence-based amplification technique and comparison with reverse transcription-PCR. Appl Environ Microbiol. 2001; 67(12):5593-600. PMC: 93348. DOI: 10.1128/AEM.67.12.5593-5600.2001. View

4.
Mukomolov S, Kontio M, Zheleznova N, Jokinen S, Sinayskaya E, Stalevskaya A . Increased circulation of hepatitis A virus genotype IIIA over the last decade in St Petersburg, Russia. J Med Virol. 2012; 84(10):1528-34. DOI: 10.1002/jmv.23378. View

5.
Hernandez F, Monge R, Jimenez C, Taylor L . Rotavirus and hepatitis A virus in market lettuce (Latuca sativa) in Costa Rica. Int J Food Microbiol. 1997; 37(2-3):221-3. DOI: 10.1016/s0168-1605(97)00058-5. View