Influenza Virus Vaccination and Kidney Graft Rejection: Causality or Coincidence

Overview

Journal Clin Kidney J

Publisher Oxford University Press

Specialty Nephrology

Date 2015 Jun 3

PMID 26034595

Citations 7

Authors

Anne Sophie Lind Fischer

Bjarne Kuno Moller

Soren Krag

Bente Jespersen

Affiliations

Soon will be listed here.

Abstract

Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had different native diseases and were all vaccinated in the same season of 2009-10. The time span from vaccination to decline of kidney function is shorter than the time to diagnosis since the three patients only had blood tests every 3 months or when symptoms became severe. These reports do not justify a change of current recommendations regarding influenza vaccination in renal transplant recipients, but they support the continued attention and registration of vaccinations to monitor side effects.

Citing Articles

Vaccination for solid organ transplanted patients: Recommendations, efficacy, and safety.

Velikova T, Gerasoudis S, Batselova H World J Transplant. 2024; 14(4):92172.

PMID: 39697451 PMC: 11438943. DOI: 10.5500/wjt.v14.i4.92172.

De Novo Biopsy-Proven Glomerular Disease Following COVID-19 Vaccination.

Chen C, Chiu Y, Chen B, Wu M, Tsai S J Clin Med. 2024; 13(15).

PMID: 39124761 PMC: 11313347. DOI: 10.3390/jcm13154494.

IgA nephropathy after COVID-19 vaccination and analysis of reported cases.

Mima A, Lee S Heliyon. 2023; 9(6):e17206.

PMID: 37332909 PMC: 10266892. DOI: 10.1016/j.heliyon.2023.e17206.

Gross hematuria can be an impact of severe acute respiratory syndrome coronavirus 2 vaccination on immunoglobulin A nephropathy: a case report.

Kanamori H J Med Case Rep. 2022; 16(1):273.

PMID: 35818083 PMC: 9272869. DOI: 10.1186/s13256-022-03514-4.

SARS-CoV-2 Vaccines: Safety and Immunogenicity in Solid Organ Transplant Recipients and Strategies for Improving Vaccine Responses.

Grupper A, Katchman H Curr Transplant Rep. 2022; 9(1):35-47.

PMID: 35096509 PMC: 8783189. DOI: 10.1007/s40472-022-00359-0.

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